| Tag | Content |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | ATP-dependent zinc metalloprotease FtsH |
Protein Synonyms/Alias | |
Gene Name | ftsH |
Gene Synonyms/Alias | SCO3404 |
Created Date | 3-June-2014 |
Organism | Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) |
NCBI Taxa ID | 100226 |
Phosphorylation | Position | Peptide | Code | Type | References | | 668 | APEDRPESMWIVLAV | S | HTP | [1] | | 650 | AISTAKSTTVEPAPA | T | HTP | [1] | | 649 | AAISTAKSTTVEPAP | S | HTP | [1] | | 651 | ISTAKSTTVEPAPAP | T | HTP | [1] | |
Reference | [1]Phosphoproteome analysis of Streptomyces development reveals extensive protein phosphorylation accompanying bacterial differentiation. Manteca A,Ye J,Sánchez J,Jensen ON J. Proteome Res. 2011, Dec, 2;10(12):5481-92. [ PMID:21999169] |
Functional Description From UniProt | FUNCTION: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) |
| TRANSMEM 1 21 Helical; (By similarity)
TRANSMEM 108 128 Helical; (By similarity) |
| ATP-binding; Cellcycle; Celldivision; Cellmembrane; Completeproteome; Hydrolase; Membrane; Metal-binding; Metalloprotease; Nucleotide-binding; Protease; Referenceproteome; Transmembrane; Transmembranehelix; Zinc |
Protein Sequence | MWIVLAVLAV VVLMQVVGSS GGYKTVDTGQ VVQAINDNRV ESAKLTTGDE QTIKVQLKDG 60
QKVEGSSKIQ ASYIGDQGVT LANTLQNKYQ DKQIPDGYTV SPSKQNPFVG ILLSLLPFVL 120
IVVVFLFLMN QMQGGGSRVM NFGKSKAKLI TKDTPKTTFS DVAGSDEAVE ELHEIKEFLQ 180
EPAKFQAVGA KIPKGVLLYG PPGTGKTLLA RAVAGEAGVP FYSISGSDFV EMFVGVGASR 240
VRDLFEQAKA NAPAIVFVDE IDAVGRHRGA GLGGGHDERE QTLNQLLVEM DGFDVKGGVI 300
LIAATNRPDI LDPALLRPGR FDRQIAVDRP DMQGRLEILK VHQKGKPVAP DVDLSAVARR 360
TPGMTGADLA NVLNEAALLT ARSDQKLIDN HMLDEAIDRV VAGPQKRTRI MSDKEKKITA 420
YHEGGHALVA AASPNSDPVH KITILSRGRA LGYTMVLPDE DKYSTTRNEM LDQLAYMLGG 480
RAAEELVFHD PTTGAANDIE KATGLARAMV TQYGMTERLG AIKFGGDNSE PFLGREMAHQ 540
RDYSEEVAAL VDEEVKKLIE TAHNEAWEIL VENRDVLDNL VLALLEKETL GKEEIAEVFS 600
QIVKRPARPA WTGSSRRTPS TRPPVLSPKE LALTNGANGA TAAISTAKST TVEPAPAPER 660
APEDRPES 668 |
| GO:0016021 C:integral component of membrane IEA:UniProtKB-KW GO:0005886 C:plasma membrane IEA:UniProtKB-SubCell GO:0005524 F:ATP binding IEA:UniProtKB-HAMAP GO:0016887 F:ATPase activity IEA:UniProtKB-HAMAP GO:0004222 F:metalloendopeptidase activity IEA:InterPro GO:0008270 F:zinc ion binding IEA:UniProtKB-HAMAP GO:0051301 P:cell division IEA:UniProtKB-KW GO:0030163 P:protein catabolic process IEA:UniProtKB-HAMAP |
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