※ Protein Information
Tag Content
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Proteasome subunit alpha 1
Protein Synonyms/Alias
 
Gene Name
 psmA1
Gene Synonyms/Alias
 psmA; OrderedLocusNames=HVO_1091
Created Date
 3-June-2014
Organism
 Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii)
NCBI Taxa ID
 309800
Phosphorylation
Position
Peptide
Code
Type
References
147 IGGVENGTPRLYETD T HTP [1]
Reference
 [1]Phosphorylation and methylation of proteasomal proteins of the haloarcheon Haloferax volcanii.
 Humbard MA,Reuter CJ,Zuobi-Hasona K,Zhou G,Maupin-Furlow JA
 Archaea 2010;:481725. [PMID:20671954]
Functional Description From UniProt
 FUNCTION: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation The H.volcanii alpha1-beta proteasome is able to cleave oligopeptides after Phe, Tyr and Trp, poorly after Glu but not after Arg. Thus, displays chymotrypsin-like activity, low caspase- like activity but no trypsin-like activity
Sequence Annotation From UniProt
 MOD_RES 1 1 N-acetylmethionine; alternate
Key Word From UniProt
 Acetylation; Completeproteome; Cytoplasm; Directproteinsequencing; Hydrolase; Protease; Proteasome; Referenceproteome; Threonineprotease
Protein Sequence
 MQGQAQQQAY DRGITIFSPD GRLYQVEYAR EAVKRGTASI GVRTPEGVVL AADKRSRSPL 60
 MEPTSVEKIH KADDHIGIAS AGHVADARQL IDFARRQSQV NRLRYGEPIG IETLTKEVTD 120
 HIQQYTQVGG ARPFGVALLI GGVENGTPRL YETDPSGTPY EWKAVSIGAD RGDHQEHLEE 180
 NFRDDLTLDE GIELALEAIA STSDEGTAPD GVDVATVSAE TERFVELSND EIESYLEAND 240
 LLATEDDEQT EE 252
  GO:0005737   C:cytoplasm IEA:UniProtKB-SubCell
  GO:0019773   C:proteasome core complex, alpha-subunit complex IDA:UniProtKB
  GO:0004175   F:endopeptidase activity IDA:UniProtKB
  GO:0004298   F:threonine-type endopeptidase activity IEA:UniProtKB-KW
  GO:0010498   P:proteasomal protein catabolic process IDA:UniProtKB
  GO:0006511   P:ubiquitin-dependent protein catabolic process IEA:InterPro
  IPR019982   Proteasome_asu_arc.
  IPR000426   Proteasome_asu_N.
  IPR023332   Proteasome_suA-type.
  IPR001353   Proteasome_sua/b.
  PF00227   Proteasome.
  PF10584   Proteasome_A_N.
  SM00948   Proteasome_A_N.
  PS00388   PROTEASOME_ALPHA_1.
  PS51475   PROTEASOME_ALPHA_2.