| Tag | Content |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit |
Protein Synonyms/Alias | DHOD B; DHODase B; DHOdehase B |
Gene Name | pyrD |
Gene Synonyms/Alias | SSO0610; ORFNames=C08_040 |
Created Date | 3-June-2014 |
Organism | Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) |
NCBI Taxa ID | 273057 |
Phosphorylation | Position | Peptide | Code | Type | References | | 37 | ICEKYKPSAITTKTV | S | HTP | [1] | | 40 | KYKPSAITTKTVTLN | T | HTP | [1] | | 41 | YKPSAITTKTVTLNP | T | HTP | [1] | | 34 | VETICEKYKPSAITT | Y | HTP | [1] | |
Reference | [1]Change of carbon source causes dramatic effects in the phospho-proteome of the archaeon Sulfolobus solfataricus. Esser D,Pham TK,Reimann J,Albers SV,Siebers B,Wright PC J. Proteome Res. 2012, Oct, 5;11(10):4823-33. [ PMID:22639831] |
Functional Description From UniProt | FUNCTION: Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor (By similarity) |
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| Completeproteome; Cytoplasm; Flavoprotein; FMN; NAD; Oxidoreductase; Pyrimidinebiosynthesis; Referenceproteome |
Protein Sequence | MITIKNITLN DPLIIASGII PDVPNYVETI CEKYKPSAIT TKTVTLNPLE PHKPPTVIKL 60
HDGIYMNAIG LGNPGAKAIN EIGVLCPLIV SVGGSSINEI KEVVEVVQSK AKIIEINVSS 120
PNRKGYGESL SKLIGDIIES VKSVTKLPVF VKLGPWDNVI ELAGKALEKG ADGLTLINTI 180
KGLIIDVETF KPILYYGTGG VSGRCLYPIA LRIIKDVYEE YGVDIIGVGG VYDWTDVIGM 240
LAAGAKLVGL GTVLIEKGFS VIEEIRKGLQ SYLLEKGLKF EDIIGISVRK 290 |
| GO:0005737 C:cytoplasm IEA:UniProtKB-SubCell GO:0004158 F:dihydroorotate oxidase activity IEA:InterPro GO:0004589 F:orotate reductase (NADH) activity IEA:UniProtKB-EC GO:0006207 P:'de novo' pyrimidine nucleobase biosynthetic process IEA:InterPro GO:0044205 P:'de novo' UMP biosynthetic process IEA:UniProtKB-UniPathway |
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