※ Protein Information
Tag Content
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Proline--tRNA ligase
Protein Synonyms/Alias
 ProRS
Gene Name
 proS
Gene Synonyms/Alias
 SSO0569
Created Date
 3-June-2014
Organism
 Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
NCBI Taxa ID
 273057
Phosphorylation
Position
Peptide
Code
Type
References
4 ****MQITREKWSKN T HTP [1]
Reference
 [1]Change of carbon source causes dramatic effects in the phospho-proteome of the archaeon Sulfolobus solfataricus.
 Esser D,Pham TK,Reimann J,Albers SV,Siebers B,Wright PC
 J. Proteome Res. 2012, Oct, 5;11(10):4823-33. [PMID:22639831]
Functional Description From UniProt
 FUNCTION: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) (By similarity)
Sequence Annotation From UniProt
 
Key Word From UniProt
 Aminoacyl-tRNAsynthetase; ATP-binding; Completeproteome; Cytoplasm; Ligase; Nucleotide-binding; Proteinbiosynthesis; Referenceproteome
Protein Sequence
 MQITREKWSK NFSEWFDWVL REGEFYDYGR YPIKGMGVWM PYGFKLRQNI IGIIRNFLDS 60
 TGHEEVLFPL LIPEDLLRRE STHIKGFEEE VFWVTKGGST DLDVKLALRP TSEVAITTME 120
 NLWLKSYKQL PKKYYQIVSV FRYETKATRP MIRLREITTF KEAHTVHETY DDAQKQVEEA 180
 IEIYKKIFDT LTIPYVLSER PEWDRFAGAL HTYAFDTIMP DGRAMQIGTV HHLGQNFSKA 240
 LDFKIQKKDG SLDYPHQTSY GISDRAVASV IAIHGDDHGP VLPPSVAPIK VVVIPIPAKN 300
 EEETQQVMKY SIEICEMFNK NNITCLTDQD TEKTPGEKFY IWEIKGVPIR LEIGPRELIS 360
 GTVFIKRRDN FKSYTVRKEE AINKIKELLN EIQEDLRRKA WEDLKSRIEY SNDIEKAKKI 420
 LGNNSGIVEV PWCGSNECGL KIEELTNARV LGYPIEKREV NDKCVICKMN AKTVLRIAKT 480
 Y 481
  GO:0005737   C:cytoplasm IEA:UniProtKB-SubCell
  GO:0005524   F:ATP binding IEA:UniProtKB-KW
  GO:0004827   F:proline-tRNA ligase activity IEA:UniProtKB-EC
  GO:0006433   P:prolyl-tRNA aminoacylation IEA:InterPro
  IPR002314   aa-tRNA-synt_IIb_cons-dom.
  IPR006195   aa-tRNA-synth_II.
  IPR004154   Anticodon-bd.
  IPR002316   Pro-tRNA-ligase_IIa.
  IPR004499   Pro-tRNA-ligase_IIa_arc-type.
  IPR016061   Pro-tRNA_ligase_II_C.
  IPR017449   Pro-tRNA_synth_II.
  PF03129   HGTP_anticodon.
  PF09180   ProRS-C_1.
  PF00587   tRNA-synt_2b.
  SM00946   ProRS-C_1.
  PS50862   AA_TRNA_LIGASE_II.
  PR01046   TRNASYNTHPRO.