| Tag | Content |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Cobalamin synthase |
Protein Synonyms/Alias | |
Gene Name | cobS |
Gene Synonyms/Alias | SCO2177 |
Created Date | 3-June-2014 |
Organism | Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) |
NCBI Taxa ID | 100226 |
Phosphorylation | Position | Peptide | Code | Type | References | | 6 | **MLRTPSPDGLRFA | S | HTP | [1] | |
Reference | [1]Phosphoproteome analysis of Streptomyces development reveals extensive protein phosphorylation accompanying bacterial differentiation. Manteca A,Ye J,Sánchez J,Jensen ON J. Proteome Res. 2011, Dec, 2;10(12):5481-92. [ PMID:21999169] |
Functional Description From UniProt | FUNCTION: Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity) |
| TRANSMEM 41 61 Helical; (By similarity)
TRANSMEM 62 82 Helical; (By similarity)
TRANSMEM 112 132 Helical; (By similarity)
TRANSMEM 139 161 Helical; (By similarity)
TRANSMEM 173 193 Helical; (By similarity)
TRANSMEM 207 227 Helical; (By similarity)
TRANSMEM 239 259 Helical; (By similarity) |
| Cellmembrane; Cobalaminbiosynthesis; Completeproteome; Membrane; Referenceproteome; Transferase; Transmembrane; Transmembranehelix |
Protein Sequence | MLRTPSPDGL RFAFGTLTVL PVKVTRWDRD AARGGMLCAP LAGLAVGAAA AAAGLLLLAL 60
GAGTLLAAVA TAAVPAVLTR GLHLDGLADT ADGLGSGKPA EDALRIMKQS DIGPFGVLAL 120
LFTLLAQVAA LAQAYDGSWA RGALAAVVSA TAARLALTTA ARTGVPAARP EGLGAAVAGV 180
VPAGGALAAT AAVTLAGAAA GAYLGPYDAL RTALAVVCAV AVAELLLRHC VRRFGGVTGD 240
VFGGVAETAA TTALVVLVLG 260 |
| GO:0016021 C:integral component of membrane IEA:UniProtKB-KW GO:0005886 C:plasma membrane IEA:UniProtKB-SubCell GO:0008818 F:cobalamin 5'-phosphate synthase activity IEA:InterPro GO:0015420 F:cobalamin-transporting ATPase activity IEA:UniProtKB-HAMAP GO:0009236 P:cobalamin biosynthetic process IEA:UniProtKB-UniPathway |
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