※ Protein Information
Tag Content
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 RNA polymerase-binding protein RbpA
Protein Synonyms/Alias
 
Gene Name
 rbpA
Gene Synonyms/Alias
 SCO1421
Created Date
 3-June-2014
Organism
 Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
NCBI Taxa ID
 100226
Phosphorylation
Position
Peptide
Code
Type
References
91 DMLMERRTREELEEV T HTP [1]
Reference
 [1]Phosphoproteome analysis of Streptomyces development reveals extensive protein phosphorylation accompanying bacterial differentiation.
 Manteca A,Ye J,Sánchez J,Jensen ON
 J. Proteome Res. 2011, Dec, 2;10(12):5481-92. [PMID:21999169]
Functional Description From UniProt
 FUNCTION: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. Stimulates transcription from several principal sigma factor HrdB (SigA)-dependent promoters but not from a SigR- dependent promoter. Stimulation occurs in the presence of the transcription initiation inhibitor rifampicin (Rif)
Sequence Annotation From UniProt
 
Key Word From UniProt
 3D-structure; Antibioticresistance; Completeproteome; Directproteinsequencing; Metal-binding; Referenceproteome; Transcription; Transcriptionregulation; Zinc
Protein Sequence
 MSERALRGTR LVVTSYETDR GIDLAPRQAV EYACEKGHRF EMPFSVEAEI PPEWECKVCG 60
 AQALLVDGDG PEEKKAKPAR THWDMLMERR TREELEEVLE ERLAVLRSGA MNIAVHPRDS 120
 RKSA 124
  GO:0001108   F:bacterial-type RNA polymerase holo enzyme binding IDA:UniProtKB
  GO:0008270   F:zinc ion binding IMP:UniProtKB
  GO:0045893   P:positive regulation of transcription, DNA-templated IDA:UniProtKB
  GO:0046677   P:response to antibiotic IEA:UniProtKB-KW
  GO:0006351   P:transcription, DNA-templated IEA:UniProtKB-KW
  IPR025182   RNApol-bd_RbpA.
  PF13397   DUF4109.