UniProt Accession

 NUOE_PSEAE;  Q9I0J8

Genbank Protein ID

 AE004091

Genbank Nucleotide ID

 AAG06028.1

Protein Name

 NADH-quinone oxidoreductase subunit E

Protein Synonyms/Alias

 

Gene Name

 nuoE

Gene Synonyms/Alias

 PA2640

Created Date

 3-June-2014

Organism

 Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)

NCBI Taxa ID

 208964

Phosphorylation

Reference

 [1]Ser/Thr/Tyr phosphoproteome analysis of pathogenic and non-pathogenic Pseudomonas species.
 Ravichandran A,Sugiyama N,Tomita M,Swarup S,Ishihama Y
 Proteomics 2009, May;9(10):2764-75. [PMID:19405024]

Functional Description From UniProt

 FUNCTION: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)

Sequence Annotation From UniProt

 

Key Word From UniProt

 2Fe-2S; Completeproteome; Iron; Iron-sulfur; Metal-binding; NAD; Oxidoreductase; Quinone; Referenceproteome; Ubiquinone

Protein Sequence

  GO:0045272   C:plasma membrane respiratory chain complex I IBA:RefGenome
  GO:0051537   F:2 iron, 2 sulfur cluster binding IEA:UniProtKB-KW
  GO:0009055   F:electron carrier activity IBA:RefGenome
  GO:0046872   F:metal ion binding IEA:UniProtKB-KW
  GO:0008137   F:NADH dehydrogenase (ubiquinone) activity IBA:RefGenome
  GO:0048038   F:quinone binding IEA:UniProtKB-KW
  GO:0022904   P:respiratory electron transport chain IBA:RefGenome

  IPR002023   NuoE-like.
  IPR012336   Thioredoxin-like_fold.

  PF01257   2Fe-2S_thioredx.

  PS01099   COMPLEX1_24K.