Tag | Content |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Phosphocarrier protein HPr |
Protein Synonyms/Alias | |
Gene Name | ptsH |
Gene Synonyms/Alias | |
Created Date | 3-June-2014 |
Organism | Bacillus thuringiensis subsp. israelensis |
NCBI Taxa ID | 1430 |
Phosphorylation | Position | Peptide | Code | Type | References | 45 | GKNVNLKSIMGVMSL | S | LTP | [1],UniProt | |
Reference | [1]Loss of catabolite repression function of HPr, the phosphocarrier protein of the bacterial phosphotransferase system, affects expression of the cry4A toxin gene in Bacillus thuringiensis subsp. israelensis. Khan SR,Banerjee-Bhatnagar N J. Bacteriol. 2002, Oct;184(19):5410-7. [ PMID:12218029] |
Functional Description From UniProt | FUNCTION: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the permease (enzymes II/III) |
| MOD_RES 14 14 Tele-phosphohistidine; alternate MOD_RES 45 45 Phosphoserine; by HPrK/P |
| Cytoplasm; Directproteinsequencing; Kinase; Phosphoprotein; Phosphotransferasesystem; Serine/threonine-proteinkinase; Sugartransport; Transcription; Transcriptionregulation; Transferase; Transport |
Protein Sequence | MEKIFKVTSD SGIHARPATL LVNTASKFGS DINLEYNGKN VNLKSIMGVM SLGIQQNAEI 60 KITANGDDAA QALAAIEETM KNEGLGE 87 |
| GO:0005737 C:cytoplasm IEA:UniProtKB-SubCell GO:0004674 F:protein serine/threonine kinase activity IEA:UniProtKB-KW GO:0005351 F:sugar:hydrogen symporter activity IEA:InterPro GO:0009401 P:phosphoenolpyruvate-dependent sugar phosphotransferase system IEA:UniProtKB-KW GO:0006355 P:regulation of transcription, DNA-templated IEA:UniProtKB-KW GO:0006351 P:transcription, DNA-templated IEA:UniProtKB-KW |
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