※ Protein Information
Tag Content
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Phosphocarrier protein HPr
Protein Synonyms/Alias
 
Gene Name
 ptsH
Gene Synonyms/Alias
 LL0117; ORFNames=L120335
Created Date
 3-June-2014
Organism
 Lactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis)
NCBI Taxa ID
 272623
Phosphorylation
Position
Peptide
Code
Type
References
52 KSIMGVMSLGVGQGA S HTP [1]
46 GKSVNLKSIMGVMSL S HTP [1],UniProt
Reference
 [1]The Ser/Thr/Tyr phosphoproteome of Lactococcus lactis IL1403 reveals multiply phosphorylated proteins.
 Soufi B,Gnad F,Jensen PR,Petranovic D,Mann M,Mijakovic I,Macek B
 Proteomics 2008, Sep;8(17):3486-93. [PMID:18668697]
Functional Description From UniProt
 FUNCTION: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the permease (enzymes II/III) (By similarity)
Sequence Annotation From UniProt
 MOD_RES 46 46 Phosphoserine; by HPrK/P
Key Word From UniProt
 Completeproteome; Cytoplasm; Kinase; Phosphoprotein; Phosphotransferasesystem; Referenceproteome; Serine/threonine-proteinkinase; Sugartransport; Transcription; Transcriptionregulation; Transferase; Transport
Protein Sequence
 MASKEFHIVV ETGIHARPAT LLVHTASKFT SEITLEYKGK SVNLKSIMGV MSLGVGQGAD 60
 VTISAEGADA DDAISTIAET MTKEGLAE 88
  GO:0005737   C:cytoplasm IEA:UniProtKB-SubCell
  GO:0004674   F:protein serine/threonine kinase activity IEA:UniProtKB-KW
  GO:0005351   F:sugar:hydrogen symporter activity IEA:InterPro
  GO:0009401   P:phosphoenolpyruvate-dependent sugar phosphotransferase system IEA:UniProtKB-KW
  GO:0006355   P:regulation of transcription, DNA-templated IEA:UniProtKB-KW
  GO:0006351   P:transcription, DNA-templated IEA:UniProtKB-KW
  IPR000032   HPr_prot-like.
  IPR001020   PTS_HPr_His_P_site.
  IPR002114   PTS_HPr_Ser_P_site.
  PF00381   PTS-HPr.
  PS51350   PTS_HPR_DOM.
  PS00369   PTS_HPR_HIS.
  PS00589   PTS_HPR_SER.
  PR00107   PHOSPHOCPHPR.