| Tag | Content |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Transcription elongation factor GreA |
Protein Synonyms/Alias | |
Gene Name | greA |
Gene Synonyms/Alias | SCO4965; ORFNames=2SCK31.25c |
Created Date | 3-June-2014 |
Organism | Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) |
NCBI Taxa ID | 100226 |
Phosphorylation | Position | Peptide | Code | Type | References | | 4 | ****MTQTSENVTWL | T | HTP | [1] | |
Reference | [1]Phosphoproteome analysis of Streptomyces development reveals extensive protein phosphorylation accompanying bacterial differentiation. Manteca A,Ye J,Sánchez J,Jensen ON J. Proteome Res. 2011, Dec, 2;10(12):5481-92. [ PMID:21999169] |
Functional Description From UniProt | FUNCTION: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) |
| COILED 55 78 Potential |
| Coiledcoil; Completeproteome; DNA-binding; Referenceproteome; Transcription; Transcriptionregulation |
Protein Sequence | MTQTSENVTW LTQEAYNKLK EELEYLTGPA RTEISAKIAA AREEGDLREN GGYHAAKEEQ 60
GKQELRVRQL TQLLESAKVG EAPAADGVVA PGMVVTIAFD GDEDDTLTFL LASREYASSD 120
IETYSPQSPL GSGVLGHKVG DDAQYELPNG KPASVRILKA EPYNG 165 |
| GO:0003677 F:DNA binding IEA:UniProtKB-KW GO:0032784 P:regulation of DNA-templated transcription, elongation IEA:InterPro GO:0006351 P:transcription, DNA-templated IEA:UniProtKB-KW |
| |
| |
| |
| |
| |
