Tag | Content |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Methionine aminopeptidase |
Protein Synonyms/Alias | MAP; MetAP |
Gene Name | map |
Gene Synonyms/Alias | SP_1084 |
Created Date | 3-June-2014 |
Organism | Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) |
NCBI Taxa ID | 170187 |
Phosphorylation | Position | Peptide | Code | Type | References | 126 | NVEQMKKYTQSYSGG | Y | LTP | [1] | |
Reference | [1]Discovery of a new genetic variant of methionine aminopeptidase from Streptococci with possible post-translational modifications: biochemical and structural characterization. Arya T,Kishor C,Saddanapu V,Reddi R,Addlagatta A PLoS ONE 2013;8(10):e75207. [ PMID:24124477] |
Functional Description From UniProt | FUNCTION: Removes the N-terminal methionine from nascent proteins The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed (By similarity) |
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| Aminopeptidase; Completeproteome; Hydrolase; Metal-binding; Protease. |
Protein Sequence | MITLKSAREI EAMDKAGDFL ASIHIGLRDL IKPGVDMWEV EEYVRRRCKE ENFLPLQIGV 60 DGAMMDYPYA TCCSLNDEVA HAFPRHYILK DGDLLKVDMV LGGPIAKSDL NVSKLNFNNV 120 EQMKKYTQSY SGGLADSCWA YAVGTPSEEV KNLMDVTKEA MYKGIEQAVV GNRIGDIGAA 180 IQEYAESRGY GVVRDLVGHG VGPTMHEEPM VPNYGIAGRG LRLREGMVLT IEPMINTGDW 240 EIDTDMKTGW AHKTIDGGLS CQYEHQFVIT KDGPVILTSQ GEEGTY 286 |
| GO:0046872 F:metal ion binding IEA:UniProtKB-HAMAP GO:0070006 F:metalloaminopeptidase activity IEA:UniProtKB-HAMAP GO:0070084 P:protein initiator methionine removal IEA:UniProtKB-HAMAP |
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