| Tag | Content |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Chaperone protein ClpB |
Protein Synonyms/Alias | |
Gene Name | clpB |
Gene Synonyms/Alias | CA_C0959 |
Created Date | 3-June-2014 |
Organism | Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787) |
NCBI Taxa ID | 272562 |
Phosphorylation | Position | Peptide | Code | Type | References | | 643 | IRIDMSEYMEKYSVS | Y | HTP | [1] | | 641 | NIIRIDMSEYMEKYS | S | HTP | [1] | |
Reference | [1]Phosphoproteomic investigation of a solvent producing bacterium Clostridium acetobutylicum. Bai X,Ji Z Appl. Microbiol. Biotechnol. 2012, Jul;95(1):201-11. [ PMID:22627760] |
Functional Description From UniProt | FUNCTION: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity) |
| COILED 395 529 By similarity |
| ATP-binding; Chaperone; Coiledcoil; Completeproteome; Cytoplasm; Nucleotide-binding; Referenceproteome; Repeat; Stressresponse |
Protein Sequence | MDVDKLTLKV QQAINDCQTI AVRYNHQQID TIHLFMAIIS QEDGLIPNIL GKMGADVETV 60
KRDTEAELDR MPKVLGEGAQ NASIYATRRF EEVFVRGEKI SRDFKDLYIS VEHVMLALMD 120
IDSGAIKSIL DKNNISKKEF LKALREVRGN QRVDTSDPEG TYDALNKYGR DLVKDAKKHK 180
LDPVIGRDEE IRRVIRILSR RTKNNPVLIG EPGVGKTAIV EGLAERIVRG DVPEGLKNKI 240
IFSLDMGSLV AGAKYRGEFE ERLKAVLKEV ERSEGKIILF IDEIHTIVGA GKTEGAMDAG 300
NIIKPMLARG ELHCIGATTF DEYRKYIEKD KALERRFQKV QIDEPTVDDA ISILRGLKER 360
FEIHHGVRIH DNAIVAAAKL SDRYITGRFL PDKAIDLIDE AGAMVRMEID SMPTELDMLK 420
RKIFQMEIEK EALSKESDKF SRERLESIQK ELSDLKDKDK AMTAKYDKEK AQIQGIKELK 480
TKLDEIRGQI EKAEREYDLN KAAELKYGEV PKLEHEIEEK ENLIKQNGQN AMLKEEVTEE 540
QVSNIVSKWT GIPVSKLVEG ERNKLMRLSD ELEKRVVGQT EAVKSVADAV IRARAGLKDM 600
SKPIGSFIFL GPTGVGKTEL AKTLARVMFD SEDNIIRIDM SEYMEKYSVS RLIGSPPGYV 660
GYEEGGQLTE AVRRKPYSVI LFDEIEKAHS DVFNIFLQIF DDGRLTDNKG NTIDFKNSII 720
IMTSNIGSEH LLNNKGVSNV DEETKDKVMN ELKGRFKPEF LNRLDDIIMF KPLSINEIGK 780
IIDIFLENIK SKLKEKNIKI DIAEEAKKII AEEGYDPVYG ARPLKRYIEN TIETHIAKMF 840
ISGEISEGDI LKIEGSDSKL TIVKK 865 |
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