| Tag | Content |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | S-adenosylmethionine synthase |
Protein Synonyms/Alias | AdoMet synthase |
Gene Name | metK |
Gene Synonyms/Alias | CA_C2856 |
Created Date | 3-June-2014 |
Organism | Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787) |
NCBI Taxa ID | 272562 |
Phosphorylation | Position | Peptide | Code | Type | References | | 251 | PQGDSGLTGRKIIVD | T | HTP | [1] | |
Reference | [1]Phosphoproteomic investigation of a solvent producing bacterium Clostridium acetobutylicum. Bai X,Ji Z Appl. Microbiol. Biotechnol. 2012, Jul;95(1):201-11. [ PMID:22627760] |
Functional Description From UniProt | FUNCTION: Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme (By similarity) |
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| ATP-binding; Cobalt; Completeproteome; Cytoplasm; Magnesium; Metal-binding; Nucleotide-binding; One-carbonmetabolism; Potassium; Referenceproteome; Transferase |
Protein Sequence | MRKLFTSESV TEGHPDKICD QISDAILDAI LEKDPNGRVA CETTVTTGIV NVMGEISTNC 60
YVDIPKIVRK TVREIGYTRA KYGFDCDTCA VVTSIDEQSA DIAMGVDEAL ESKKGEMDKI 120
DAVGAGDQGM MFGYATNETK EFMPMPIALA HRLSRRLAEV RKDGTLDYLR PDGKTQVTIE 180
YEDDKPVRVD AIVISTQHGP EIGHEQIEKD LIEKVVKYVI SPELLDENTK YYINPTGRFV 240
VGGPQGDSGL TGRKIIVDTY GGYGRHGGGA FSGKDPTKVD RSAAYAARWV AKNLVAAGIA 300
DKLEIQLAYA IGVAKPVSIS VDTFGTGKIE ESKIVEIVEK VFDLRPGAII RDLNLKRPIY 360
RQVAAYGHFG RLDVELPWEQ LDRVEAIKKY L 391 |
| GO:0005737 C:cytoplasm IEA:UniProtKB-SubCell GO:0005524 F:ATP binding IEA:UniProtKB-HAMAP GO:0000287 F:magnesium ion binding IEA:UniProtKB-HAMAP GO:0004478 F:methionine adenosyltransferase activity IEA:UniProtKB-HAMAP GO:0006730 P:one-carbon metabolic process IEA:UniProtKB-HAMAP GO:0006556 P:S-adenosylmethionine biosynthetic process IEA:UniProtKB-UniPathway |
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