※ Protein Information
Tag Content
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 S-ribosylhomocysteine lyase
Protein Synonyms/Alias
 
Gene Name
 luxS
Gene Synonyms/Alias
 CA_C2942
Created Date
 3-June-2014
Organism
 Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)
NCBI Taxa ID
 272562
Phosphorylation
Position
Peptide
Code
Type
References
13 SFTVNHLTLQPGVYV T HTP [1]
Reference
 [1]Phosphoproteomic investigation of a solvent producing bacterium Clostridium acetobutylicum.
 Bai X,Ji Z
 Appl. Microbiol. Biotechnol. 2012, Jul;95(1):201-11. [PMID:22627760]
Functional Description From UniProt
 FUNCTION: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
Sequence Annotation From UniProt
 
Key Word From UniProt
 Autoinducersynthesis; Completeproteome; Iron; Lyase; Metal-binding; Quorumsensing; Referenceproteome
Protein Sequence
 MEKIASFTVN HLTLQPGVYV SRKDKFGDVV ITTFDIRMTS PNEEPVMNTA EVHTIEHLGA 60
 TFLRNHGTYA EKTVYFGPMG CRTGFYLILQ GDYTSNDIVP LLREMYKFIA DFKGEVPGAA 120
 ARDCGNYLDM NLPMANYWGK KFSALLDNIS EDRLNYPE 158
  GO:0005506   F:iron ion binding IEA:InterPro
  GO:0043768   F:S-ribosylhomocysteine lyase activity IEA:UniProtKB-HAMAP
  GO:0009372   P:quorum sensing IEA:UniProtKB-HAMAP
  IPR011249   Metalloenz_LuxS/M16.
  IPR003815   S-ribosylhomocysteinase.
  PF02664   LuxS.
  PR01487   LUXSPROTEIN.