| Tag | Content |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | DNA protection during starvation protein |
Protein Synonyms/Alias | |
Gene Name | dps |
Gene Synonyms/Alias | flp, fri; OrderedLocusNames=lmo0943 |
Created Date | 3-June-2014 |
Organism | Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) |
NCBI Taxa ID | 169963 |
Phosphorylation | Position | Peptide | Code | Type | References | | 3 | *****MKTINSVDTK | T | HTP | [1] | |
Reference | [1]Analysis of the serine/threonine/tyrosine phosphoproteome of the pathogenic bacterium Listeria monocytogenes reveals phosphorylated proteins related to virulence. Misra SK,Milohanic E,Aké F,Mijakovic I,Deutscher J,Monnet V,Henry C Proteomics 2011, Nov;11(21):4155-65. [ PMID:21956863] |
Functional Description From UniProt | FUNCTION: Protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction. Does not bind to DNA (By similarity). Dps is important for full resistance to heat and cold shocks and is essential for full virulence of this bacterium. It seems to play a direct or indirect role on the production and/or stability of listeriolysin O |
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| 3D-structure; Completeproteome; Cytoplasm; Directproteinsequencing; Iron; Ironstorage; Metal-binding; Oxidoreductase; Referenceproteome; Virulence |
Protein Sequence | MKTINSVDTK EFLNHQVANL NVFTVKIHQI HWYMRGHNFF TLHEKMDDLY SEFGEQMDEV 60
AERLLAIGGS PFSTLKEFLE NASVEEAPYT KPKTMDQLME DLVGTLELLR DEYQQGIELT 120
DKEGDNVTND MLIAFKASID KHIWMFKAFL GKAPLE 156 |
| GO:0005737 C:cytoplasm IEA:UniProtKB-SubCell GO:0008199 F:ferric iron binding IEA:InterPro GO:0016722 F:oxidoreductase activity, oxidizing metal ions IEA:InterPro GO:0006879 P:cellular iron ion homeostasis IEA:UniProtKB-KW GO:0009405 P:pathogenesis IEA:UniProtKB-KW GO:0006950 P:response to stress IEA:InterPro |
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