| Tag | Content |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Valine--tRNA ligase |
Protein Synonyms/Alias | ValRS |
Gene Name | valS |
Gene Synonyms/Alias | lmo1552 |
Created Date | 3-June-2014 |
Organism | Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) |
NCBI Taxa ID | 169963 |
Phosphorylation | Position | Peptide | Code | Type | References | | 854 | FISKAPESVVAEERL | S | HTP | [1] | | 531 | EGRKMSKSLGNGVDP | S | HTP | [1] | |
Reference | [1]Analysis of the serine/threonine/tyrosine phosphoproteome of the pathogenic bacterium Listeria monocytogenes reveals phosphorylated proteins related to virulence. Misra SK,Milohanic E,Aké F,Mijakovic I,Deutscher J,Monnet V,Henry C Proteomics 2011, Nov;11(21):4155-65. [ PMID:21956863] |
Functional Description From UniProt | FUNCTION: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a "posttransfer" editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) |
| COILED 811 847 Potential |
| Aminoacyl-tRNAsynthetase; ATP-binding; Coiledcoil; Completeproteome; Cytoplasm; Ligase; Nucleotide-binding; Proteinbiosynthesis; Referenceproteome |
Protein Sequence | MTTEHNEINM PTKYEPSNVE AGKYKWWLEK EFFKAEGNTD KEPYSIVIPP PNVTGKLHLG 60
HAWDTTLQDI ITRMKRMQGF DTLYLPGMDH AGIATQAKVE AKLKESNISR YDLGRENFVD 120
KTWEWKEEYA EFIREQWEKL GLGLDYSRER FTLDDGLSDA VKKVFVTLYN KGLIYRGQYI 180
INWDPEAKTA LSDIEVIHKD IEGSFYHLKY PLTDGSGYLE VATTRPETIP GDTAVAVHPK 240
DERYQHLIGK TIMLPILNRE IPIVADEYVE REFGSGAVKI TPAHDPNDFE VGNRHNLPRI 300
IVMHEDGTMN ENAGKYDGLD RFVARKEIIQ DFKDLGLFIK QEPHLHSVGH SERTGAVVEP 360
YLSLQWFVKM EPLAAEALEL QKTENKVNFV PARFEKTYET WMDNIHDWCI SRQLWWGHRI 420
PAWYHKETGE IYVGEKEPEN LSEWEQDEDV LDTWFSSALW PFSTMGWPDT ESPDFQHFFP 480
TNTLVTGYDI IFFWVSRMIF QSVEFTGERP FKDTLIHGLV RDSEGRKMSK SLGNGVDPIE 540
VIDKYGADSL RYTLATGSSP GQDLKFSYEK VESTWNFINK IWNASRFVLM NLDGMKYNEI 600
DLSNVTEVSD KWILTRLNET IQAVTSLGEK YEFGEVGRTL YNFIWDDFCD WYIEIAKIPL 660
YGEDEVAKQT TRSVLAYTLN ATMRLLHPFM PFVTEEIWQN LPHEGESITI AEWPKVNEQQ 720
IDTKSSTAMA TLVEVIRAVR NIRSEVNTPL SKPIVLEIKP KDTTYKEILE QNISYIERFC 780
NPEQVTISFD VEASKTAMTA VVSGAEIFIP LEALIDLNVE IARLEKELEK WNKEVARVQG 840
KLNNERFISK APESVVAEER LKEKDYLDKK ASVLERIETL KEV 883 |
| GO:0005737 C:cytoplasm IEA:UniProtKB-SubCell GO:0002161 F:aminoacyl-tRNA editing activity IEA:InterPro GO:0005524 F:ATP binding IEA:UniProtKB-HAMAP GO:0004832 F:valine-tRNA ligase activity IEA:UniProtKB-HAMAP GO:0006438 P:valyl-tRNA aminoacylation IEA:UniProtKB-HAMAP |
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