| Tag | Content |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | DNA ligase |
Protein Synonyms/Alias | |
Gene Name | ligA |
Gene Synonyms/Alias | lmo1758 |
Created Date | 3-June-2014 |
Organism | Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) |
NCBI Taxa ID | 169963 |
Phosphorylation | Position | Peptide | Code | Type | References | | 641 | VAGSDAGSKLAKAEE | S | HTP | [1] | |
Reference | [1]Analysis of the serine/threonine/tyrosine phosphoproteome of the pathogenic bacterium Listeria monocytogenes reveals phosphorylated proteins related to virulence. Misra SK,Milohanic E,Aké F,Mijakovic I,Deutscher J,Monnet V,Henry C Proteomics 2011, Nov;11(21):4155-65. [ PMID:21956863] |
Functional Description From UniProt | FUNCTION: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity) |
| |
| Completeproteome; DNAdamage; DNArepair; DNAreplication; Ligase; Magnesium; Manganese; Metal-binding; NAD; Referenceproteome; Zinc |
Protein Sequence | MADKKRYEEL INILDQYSYD YYVIDNPTVE DAEYDQKMQE LLKIEEAHPE WVTPESPSKR 60
VGGEVLEGFK KVAHDTPMLS LANAFNHEDL ADFDRRIRDK VGDDIAYMCE LKIDGLAVSL 120
QYENGKYKQG ATRGDGTIGE DITANLRTIR SIPMKLQKDY SIEVRGEAFM PKRSFQKLNE 180
IREEEGQMLF ANPRNAAAGS LRQLDTKIAA SRNLDIFLYA VADFGEMGVE THSAGLDMLE 240
TLGLKVNKER RLCSSLEEVY AYIDEWTEKR ADLAYDIDGI VLKLNNLEQQ RQMGTTVKSP 300
RWSIAYKFPA EEVPTKLLDI ELNVGRTGVI TPTAVLEPVR VAGTTVSRAS LHNEDLITEK 360
DIRIGDTVLI KKAGDIIPEV IKSITEERSG SEEPFHMPKK CPTCDSELVR LEEEVALRCI 420
NPKCPAQIKE GLIHFVSRNA MNIDGLGEKV IIQLFSQHLI KDVADLFFLS KEKLLELERM 480
GEKSVTNLLA SIEASKQNSL EKLLFGLGIR HVGAKAAKSL AVHFETMDNL KVADKETLTS 540
INDIGEKMAD SIVTYFANEE VHDLLEELKR AGVNMTYTGP KLEDMSEEEL VFAGKTVVLT 600
GKLEKLTRND AKALIESLGG NVSGSVSKKT DVVVAGSDAG SKLAKAEELA IPIWSEEDLI 660
EYLPDEGGLN E 671 |
| |
| |
| |
| |
| |
| |
