※ Protein Information
Tag Content
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Elongation factor G
Protein Synonyms/Alias
 EF-G
Gene Name
 fusA
Gene Synonyms/Alias
 fus; OrderedLocusNames=lmo2654
Created Date
 3-June-2014
Organism
 Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)
NCBI Taxa ID
 169963
Phosphorylation
Position
Peptide
Code
Type
References
679 HYEEVPKSIAEEIIK S HTP [1]
304 AARHADDSEPFSSLA S HTP [1]
319 FKVMTDPYVGRLTFF Y HTP [1]
Reference
 [1]Analysis of the serine/threonine/tyrosine phosphoproteome of the pathogenic bacterium Listeria monocytogenes reveals phosphorylated proteins related to virulence.
 Misra SK,Milohanic E,Aké F,Mijakovic I,Deutscher J,Monnet V,Henry C
 Proteomics 2011, Nov;11(21):4155-65. [PMID:21956863]
Functional Description From UniProt
 FUNCTION: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
Sequence Annotation From UniProt
 
Key Word From UniProt
 Completeproteome; Cytoplasm; Elongationfactor; GTP-binding; Nucleotide-binding; Proteinbiosynthesis; Referenceproteome
Protein Sequence
 MAREFSLEKT RNIGIMAHID AGKTTTTERI LFYTGRIHKI GETHEGASQM DWMEQEQERG 60
 ITITSAATTA QWKGYRVNII DTPGHVDFTV EVERSLRVLD GAVAVLDAQS GVEPQTETVW 120
 RQATTYGVPR VVFVNKMDKI GADFLYSVGT LHERLAANAH PIQLPIGAED TFEGIIDLIE 180
 MNALYYEDDL GNDPHIKEIP ADLKDLADEY RGKLVEAVAE LDEELMMKYL EGEEITKEEL 240
 KAGIRKGTLN VEFYPVVCGT AFKNKGVQPM LDAVLDYLPA PTDVPAINGV LPDGEEAARH 300
 ADDSEPFSSL AFKVMTDPYV GRLTFFRVYS GTLNSGSYVQ NSTKGKRERV GRILQMHANH 360
 REEISIVYAG DIAAAVGLKD TTTGDTLCDE KEQIILESME FPEPVIQVAI EPKSKADQDK 420
 MGQALAKLAE EDPTFRAETD QETGQTLISG MGELHLDILV DRMRREFRVE ANVGDPQVSY 480
 RETFRKSAQV EGKFVRQSGG RGQYGHVWIE FGPNEEGKGF EFENAIVGGV VPREYIPAVQ 540
 AGLEGALDNG VLAGYPLIDI KAKLYDGSYH DVDSNEMAFK VAASMALRNA AKKCDPVILE 600
 PMMAVEVVIP EEYLGDIMGN ITSRRGRVDG MEARGNAQVV RAFVPLANMF GYATHLRSGT 660
 QGRGVYTMQF DHYEEVPKSI AEEIIKANGG NNKED 695
  GO:0005737   C:cytoplasm IEA:UniProtKB-SubCell
  GO:0005525   F:GTP binding IEA:UniProtKB-HAMAP
  GO:0003924   F:GTPase activity IEA:InterPro
  GO:0003746   F:translation elongation factor activity IEA:UniProtKB-HAMAP
  IPR000795   EF_GTP-bd_dom.
  IPR009022   EFG_III-V.
  IPR000640   EFG_V.
  IPR027417   P-loop_NTPase.
  IPR020568   Ribosomal_S5_D2-typ_fold.
  IPR014721   Ribosomal_S5_D2-typ_fold_subgr.
  IPR005225   Small_GTP-bd_dom.
  IPR009000   Transl_B-barrel.
  IPR004540   Transl_elong_EFG/EF2.
  IPR005517   Transl_elong_EFG/EF2_IV.
  IPR004161   Transl_elong_EFTu/EF1A_2.
  PF00679   EFG_C.
  PF14492   EFG_II.
  PF03764   EFG_IV.
  PF00009   GTP_EFTU.
  PF03144   GTP_EFTU_D2.
  SM00838   EFG_C.
  SM00889   EFG_IV.
  PS00301   EFACTOR_GTP.
  PR00315   ELONGATNFCT.