※ Protein Information
Tag Content
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Serine--tRNA ligase
Protein Synonyms/Alias
 SerRS
Gene Name
 serS
Gene Synonyms/Alias
 lmo2747
Created Date
 3-June-2014
Organism
 Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)
NCBI Taxa ID
 169963
Phosphorylation
Position
Peptide
Code
Type
References
208 NRASMTGTGQLPKFE T HTP [1]
56 KSQRNEVSQEIAKLK S HTP [1]
Reference
 [1]Analysis of the serine/threonine/tyrosine phosphoproteome of the pathogenic bacterium Listeria monocytogenes reveals phosphorylated proteins related to virulence.
 Misra SK,Milohanic E,Aké F,Mijakovic I,Deutscher J,Monnet V,Henry C
 Proteomics 2011, Nov;11(21):4155-65. [PMID:21956863]
Functional Description From UniProt
 FUNCTION: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
Sequence Annotation From UniProt
 
Key Word From UniProt
 Aminoacyl-tRNAsynthetase; ATP-binding; Completeproteome; Cytoplasm; Ligase; Nucleotide-binding; Proteinbiosynthesis; Referenceproteome
Protein Sequence
 MLDVKLLRNN FDEVKQKLQN RGEDLGEFEK FGELDKRRRT LIVETEALKS QRNEVSQEIA 60
 KLKREKQDAD AKIEEMRVVG DRIKTLDIEL REIDEKLDMI LMSIPNIPHE STPVGESEDD 120
 NVEIRKWGEV RAFDFEPKAH WDLGTDLDIL DFENAAKVTG SRFVFYKKLG ARLERALINF 180
 MMDLHSNEHG YEEMLPPYMV NRASMTGTGQ LPKFEEDAFL IEAEDYFLIP TAEVPVTNYH 240
 REDILKAEDL PRKYTAFSAC FRSEAGSAGR DTRGLIRQHQ FNKVELVQFV KPEDSYVALE 300
 KLTGNAEEVL RRLELPYRVL SMCTADLGFT AAKKYDLEVW IPSYNSYREI SSCSNFESFQ 360
 ARRANIRFRR EPGSKPEYVH TLNGSGLALG RTVAAILENY QDADGSVRIP KVLQGYMGGI 420
 EKIELPK 427
  GO:0005737   C:cytoplasm IEA:UniProtKB-SubCell
  GO:0005524   F:ATP binding IEA:UniProtKB-HAMAP
  GO:0004828   F:serine-tRNA ligase activity IEA:UniProtKB-HAMAP
  GO:0016260   P:selenocysteine biosynthetic process IEA:UniProtKB-HAMAP
  GO:0097056   P:selenocysteinyl-tRNA(Sec) biosynthetic process IEA:UniProtKB-UniPathway
  GO:0006434   P:seryl-tRNA aminoacylation IEA:UniProtKB-HAMAP
  IPR002314   aa-tRNA-synt_IIb_cons-dom.
  IPR006195   aa-tRNA-synth_II.
  IPR002317   Ser-tRNA-ligase_type_1.
  IPR015866   Ser-tRNA-synth_1_N.
  IPR010978   tRNA-bd_arm.
  PF02403   Seryl_tRNA_N.
  PF00587   tRNA-synt_2b.
  PS50862   AA_TRNA_LIGASE_II.
  PR00981   TRNASYNTHSER.