UniProt Accession

 Q8XDF6_ECO57;  Q8XDF6;  Q7A9U8

Genbank Protein ID

 AE005174;  BA000007

Genbank Nucleotide ID

 AAG58753.1;  BAB37907.1

Protein Name

 tRNA (cytidine(34)-2'-O)-methyltransferase

Protein Synonyms/Alias

 

Gene Name

 yibK

Gene Synonyms/Alias

 trmL; OrderedLocusNames=ECs4484, Z5033

Created Date

 3-June-2014

Organism

 Escherichia coli O157:H7

NCBI Taxa ID

 83334

Phosphorylation

Reference

 [1]The Escherichia coli phosphotyrosine proteome relates to core pathways and virulence.
 Hansen AM,Chaerkady R,Sharma J,Díaz-Mejía JJ,Tyagi N,Renuse S,Jacob HK,Pinto SM,Sahasrabuddhe NA,Kim MS,Delanghe B,Srinivasan N,Emili A,Kaper JB,Pandey A
 PLoS Pathog. 2013;9(6):e1003403. [PMID:23785281]

Functional Description From UniProt

 FUNCTION: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)

Sequence Annotation From UniProt

 

Key Word From UniProt

 Completeproteome; Cytoplasm; Methyltransferase; S-adenosyl-L-methionine; Transferase; tRNAprocessing

Protein Sequence

  GO:0005737   C:cytoplasm IEA:UniProtKB-SubCell
  GO:0003723   F:RNA binding IEA:InterPro
  GO:0008757   F:S-adenosylmethionine-dependent methyltransferase activity IEA:UniProtKB-HAMAP
  GO:0008175   F:tRNA methyltransferase activity IEA:UniProtKB-HAMAP

  IPR001537   SpoU_MeTrfase.
  IPR016914   tRNA_cyt/urid_MeTfrase.

  PF00588   SpoU_methylase.