※ Protein Information
Tag Content
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Transcription termination factor Rho
Protein Synonyms/Alias
 
Gene Name
 rho
Gene Synonyms/Alias
 TTHA1065
Created Date
 3-June-2014
Organism
 Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
NCBI Taxa ID
 300852
Phosphorylation
Position
Peptide
Code
Type
References
191 APPKAGKTTLLKKIA T HTP [1]
Reference
 [1]Close proximity of phosphorylation sites to ligand in the phosphoproteome of the extreme thermophile Thermus thermophilus HB8.
 Takahata Y,Inoue M,Kim K,Iio Y,Miyamoto M,Masui R,Ishihama Y,Kuramitsu S
 Proteomics 2012, May;12(9):1414-30. [PMID:22589190]
Functional Description From UniProt
 FUNCTION: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
Sequence Annotation From UniProt
 
Key Word From UniProt
 ATP-binding; Completeproteome; Helicase; Hydrolase; Nucleotide-binding; Referenceproteome; RNA-binding; Transcription; Transcriptionregulation; Transcriptiontermination
Protein Sequence
 MRRKETLQET PLTYQELASK ILPELHLLAQ EAGIEGYKRM KKDQLIMALL ERQTQGEGLR 60
 LVKGYLEISQ DGYGFLTENL HNLESRVAIV SAGLIKQYAL RAGDYVVGQA RPPRENERYA 120
 TLLKVEAVNN LDPEAAKNRP RFDELTPQFP DRQIRLETTP DELSTRVIDL LAPIGRGQRG 180
 LIVAPPKAGK TTLLKKIANA VLKNEPDIKV IVLLIDERPE EVTDFRESVQ GAEVIASTFD 240
 EPPQNHIRVA EFVHERAKRI VEEGGHVMIL LDSITRLARA NNLVTPPTGR TLSGGLDSAA 300
 LYFPKRFLGA ARNIRGGGSL TILATALVET GSRMDDVIFE EFKGTGNMEL HLSRRLEERR 360
 IFPAIDILKS GTRREELLLG EEVTHKMWLL RKVLADMDPA EAMEMLLARL ARTKNNKEFL 420
 ASLAAR 426
  GO:0005524   F:ATP binding IEA:UniProtKB-HAMAP
  GO:0004386   F:helicase activity IEA:UniProtKB-HAMAP
  GO:0003723   F:RNA binding IEA:UniProtKB-HAMAP
  GO:0008186   F:RNA-dependent ATPase activity IEA:InterPro
  GO:0006353   P:DNA-templated transcription, termination IEA:UniProtKB-HAMAP
  GO:0006355   P:regulation of transcription, DNA-templated IEA:UniProtKB-KW
  IPR003593   AAA+_ATPase.
  IPR000194   ATPase_F1/V1/A1_a/bsu_nucl-bd.
  IPR012340   NA-bd_OB-fold.
  IPR027417   P-loop_NTPase.
  IPR011112   Rho_N.
  IPR011113   Rho_RNA-bd.
  IPR004665   Term_rho.
  PF00006   ATP-synt_ab.
  PF07498   Rho_N.
  PF07497   Rho_RNA_bind.
  SM00382   AAA.
  SM00959   Rho_N.