※ Protein Information
Tag Content
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Thymidylate synthase ThyX
Protein Synonyms/Alias
 TS;  TSase
Gene Name
 thyX
Gene Synonyms/Alias
 TTHA1096
Created Date
 3-June-2014
Organism
 Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
NCBI Taxa ID
 300852
Phosphorylation
Position
Peptide
Code
Type
References
92 TASVNEISGRYSILK S HTP [1]
Reference
 [1]Close proximity of phosphorylation sites to ligand in the phosphoproteome of the extreme thermophile Thermus thermophilus HB8.
 Takahata Y,Inoue M,Kim K,Iio Y,Miyamoto M,Masui R,Ishihama Y,Kuramitsu S
 Proteomics 2012, May;12(9):1414-30. [PMID:22589190]
Functional Description From UniProt
 FUNCTION: Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
Sequence Annotation From UniProt
 
Key Word From UniProt
 Completeproteome; FAD; Flavoprotein; Methyltransferase; NADP; Nucleotidebiosynthesis; Referenceproteome; Transferase
Protein Sequence
 MEGPLTIPVL DKGFVRLVDQ MGDDRAIVQA ARVSYGEGTK TVREDAALID YLMRHRHTSP 60
 FEMVVFKFHV KAPIFVARQW FRHRTASVNE ISGRYSILKE EFYEPEAFRK QAKRNKQASE 120
 GALLDEEALA LLRKVQQEAY GAYRALLEKG VAREMARMVL PLNLYTEFYW KQDLHNLFHF 180
 LKLRLAPEAQ WEIRQYARAI AEIVKERVPL AWAAFEEHLL EGAFLSRTEL RALRGLLTPE 240
 VYEKALSSLG LGGSRLKEAL EKVFGPGEAL 270
  GO:0050660   F:flavin adenine dinucleotide binding IEA:UniProtKB-HAMAP
  GO:0050797   F:thymidylate synthase (FAD) activity IEA:UniProtKB-HAMAP
  GO:0006231   P:dTMP biosynthetic process IEA:UniProtKB-HAMAP
  IPR003669   Thymidylate_synthase_ThyX.
  PF02511   Thy1.
  PS51331   THYX.