| Tag | Content |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Nitrogen regulatory protein P-II |
Protein Synonyms/Alias | |
Gene Name | glnB |
Gene Synonyms/Alias | ssl0707 |
Created Date | 3-June-2014 |
Organism | Synechocystis sp. (strain PCC 6803 / Kazusa) |
NCBI Taxa ID | 1111708 |
Phosphorylation | Position | Peptide | Code | Type | References | | 49 | QTERYRGSEYTVEFL | S | LTP | [1] | |
Reference | [1]PII is important in regulation of nitrogen metabolism but not required for heterocyst formation in the Cyanobacterium Anabaena sp. PCC 7120. Zhang Y,Pu H,Wang Q,Cheng S,Zhao W,Zhang Y,Zhao J J. Biol. Chem. 2007, Nov, 16;282(46):33641-8. [ PMID:17875643] |
Functional Description From UniProt | FUNCTION: P-II indirectly controls the transcription of the GS gene (glnA). P-II prevents NR-II-catalyzed conversion of NR-I to NR-I-phosphate, the transcriptional activator of glnA. When P-II is phosphorylated, these events are reversed. In nitrogen-limiting conditions, when the ratio of Gln to 2-ketoglutarate decreases, P- II is phosphorylated which allows the deadenylation of glutamine synthetase (GS), thus activating the enzyme (By similarity) |
| MOD_RES 49 49 Phosphoserine (Probable)
MOD_RES 51 51 O-UMP-tyrosine (By similarity) |
| 3D-structure; Completeproteome; Nucleotide-binding; Phosphoprotein; Referenceproteome; Transcription; Transcriptionregulation |
Protein Sequence | MKKVEAIIRP FKLDEVKIAL VNAGIVGMTV SEVRGFGRQK GQTERYRGSE YTVEFLQKLK 60
IEIVVDEGQV DMVVDKLVSA ARTGEIGDGK IFISPVDSVV RIRTGEKDTE AI 112 |
| GO:0030234 F:enzyme regulator activity IEA:InterPro GO:0000166 F:nucleotide binding IEA:UniProtKB-KW GO:0006808 P:regulation of nitrogen utilization IEA:InterPro GO:0006355 P:regulation of transcription, DNA-templated IEA:UniProtKB-KW GO:0006351 P:transcription, DNA-templated IEA:UniProtKB-KW |
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