※ Protein Information
Tag Content
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Phosphoribosylglycinamide formyltransferase 2
Protein Synonyms/Alias
 GART 2
Gene Name
 purT
Gene Synonyms/Alias
 Saci_0214
Created Date
 3-June-2014
Organism
 Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)
NCBI Taxa ID
 330779
Phosphorylation
Position
Peptide
Code
Type
References
207 DRELTVLTYRYPLSS T HTP [1]
Reference
 [1]Archaeal signal transduction: impact of protein phosphatase deletions on cell size, motility, and energy metabolism in Sulfolobus acidocaldarius.
 Reimann J,Esser D,Orell A,Amman F,Pham TK,Noirel J,Lindås AC,Bernander R,Wright PC,Siebers B,Albers SV
 Mol. Cell Proteomics 2013, Dec;12(12):3908-23. [PMID:24078887]
Functional Description From UniProt
 FUNCTION: Catalyzes two reactions: the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR; the second, a side reaction, is the production of acetyl phosphate and ADP from acetate and ATP (By similarity)
Sequence Annotation From UniProt
 
Key Word From UniProt
 ATP-binding; Completeproteome; Magnesium; Metal-binding; Nucleotide-binding; Purinebiosynthesis; Transferase
Protein Sequence
 MEIGTPLFEG AKKLLWLGGG ELGKEMVIEA QRMGVETVVI DRYDLAPAMH VAHRKYVVNM 60
 HDGGAIESII RKERPDAVIA EIEAINTETL SKIEMDGIKV MPNARAVKIC MDRIELRRFA 120
 AEKVKVPTTA YGFATSPEEV KKMCKDVGYP CIIKPQMSSS GHGHEVIYDE SQVEEKFKEA 180
 LTHARGKSKT VIVEEYVKID RELTVLTYRY PLSSGGVATK TIYPVEHQRP QGVYHYIESW 240
 HPATVSQDVI SKASEYATKV VNELGGFGIF GVEIMIAGNR VLFNEVAPRP HDTGLVTLVS 300
 SDISEFQVHV RSALGLPTPD VKVVTPAAAH VILASGEKWA PKYINVDKAL EIPGVQVRLF 360
 GKPVTYNERR MGIVLATGNS VEEAKEKVRK ASALILVS 398
  GO:0005524   F:ATP binding IEA:UniProtKB-HAMAP
  GO:0000287   F:magnesium ion binding IEA:InterPro
  GO:0043815   F:phosphoribosylglycinamide formyltransferase 2 activity IEA:UniProtKB-HAMAP
  GO:0004644   F:phosphoribosylglycinamide formyltransferase activity IEA:InterPro
  GO:0006189   P:'de novo' IMP biosynthetic process IEA:UniProtKB-UniPathway
  IPR011761   ATP-grasp.
  IPR003135   ATP-grasp_carboxylate-amine.
  IPR013815   ATP_grasp_subdomain_1.
  IPR013816   ATP_grasp_subdomain_2.
  IPR016185   PreATP-grasp_dom.
  IPR005862   PurT.
  PF02222   ATP-grasp.
  PS50975   ATP_GRASP.