※ Protein Information
Tag Content
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 CCA-adding enzyme
Protein Synonyms/Alias
 
Gene Name
 cca
Gene Synonyms/Alias
 Saci_1288
Created Date
 3-June-2014
Organism
 Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)
NCBI Taxa ID
 330779
Phosphorylation
Position
Peptide
Code
Type
References
229 RNTASAVSLRNIAVF S HTP [1]
224 PVDPKRNTASAVSLR T HTP [1]
Reference
 [1]Archaeal signal transduction: impact of protein phosphatase deletions on cell size, motility, and energy metabolism in Sulfolobus acidocaldarius.
 Reimann J,Esser D,Orell A,Amman F,Pham TK,Noirel J,Lindås AC,Bernander R,Wright PC,Siebers B,Albers SV
 Mol. Cell Proteomics 2013, Dec;12(12):3908-23. [PMID:24078887]
Functional Description From UniProt
 FUNCTION: Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate (By similarity)
Sequence Annotation From UniProt
 
Key Word From UniProt
 ATP-binding; Completeproteome; Magnesium; Metal-binding; Nucleotide-binding; Nucleotidyltransferase; RNArepair; RNA-binding; Transferase; tRNAprocessing
Protein Sequence
 MSVEEKVLEL IRPDDKDRER LEKVAEEVLS RLKGFDAQIQ GSFRKGTWLK GDTDIDIFVF 60
 YPKEVGKEYL REKSLKELIQ LFQDLNYEIA FAEHPYLILK INNVEVDVVP ALKIDSGEDV 120
 ITAADRTPFH TKFVTTHLDE KGKDEVRLLK QFMKGIGVYG AEIKVKGFSG YVAELLTIYY 180
 GNFRKVLESA KTWKPPIKLN LVEPKRDFDE PLQIPDPVDP KRNTASAVSL RNIAVFSLAS 240
 KIFIERPSIE FFFPTEIKAE EIIGDILLIK VEFKEKSVED IIWGQVWKNV EKLKNAIKTA 300
 GFSLIDIGAW GNSQTVKIAV QIEDKNISRY YLNQGPYFYV NGVDNFMRKN KYVWVGEDGR 360
 LYSLKKRRET NLEKIVLNNL SFKENFSVEM TWLSEINQDD KELHKFLRKR PTWMQT 416
  GO:0005524   F:ATP binding IEA:UniProtKB-HAMAP
  GO:0052929   F:ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity IEA:UniProtKB-EC
  GO:0052928   F:CTP:3'-cytidine-tRNA cytidylyltransferase activity IEA:UniProtKB-EC
  GO:0052927   F:CTP:tRNA cytidylyltransferase activity IEA:UniProtKB-EC
  GO:0000287   F:magnesium ion binding IEA:UniProtKB-HAMAP
  GO:0004810   F:tRNA adenylyltransferase activity IEA:UniProtKB-HAMAP
  GO:0000049   F:tRNA binding IEA:UniProtKB-HAMAP
  GO:0016437   F:tRNA cytidylyltransferase activity IEA:UniProtKB-HAMAP
  GO:0006955   P:immune response IEA:InterPro
  GO:0042245   P:RNA repair IEA:UniProtKB-KW
  GO:0001680   P:tRNA 3'-terminal CCA addition IEA:UniProtKB-HAMAP
  IPR006116   2-5-oligoadenylate_synth_N.
  IPR008229   CCA-adding_arc.
  IPR002934   Nucleotidyltransferase.
  IPR011068   NuclTrfase_I_C.
  IPR015329   tRNA_NucTransf2.
  PF01909   NTP_transf_2.
  PF09249   tRNA_NucTransf2.