※ Protein Information
Tag Content
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Serine--tRNA ligase
Protein Synonyms/Alias
 SerRS
Gene Name
 serS
Gene Synonyms/Alias
 Saci_1584
Created Date
 3-June-2014
Organism
 Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)
NCBI Taxa ID
 330779
Phosphorylation
Position
Peptide
Code
Type
References
447 FSGAPKEYIYPKKKP Y HTP [1]
457 PKKKPNTTSMSWSIL T HTP [1]
Reference
 [1]Archaeal signal transduction: impact of protein phosphatase deletions on cell size, motility, and energy metabolism in Sulfolobus acidocaldarius.
 Reimann J,Esser D,Orell A,Amman F,Pham TK,Noirel J,Lindås AC,Bernander R,Wright PC,Siebers B,Albers SV
 Mol. Cell Proteomics 2013, Dec;12(12):3908-23. [PMID:24078887]
Functional Description From UniProt
 FUNCTION: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
Sequence Annotation From UniProt
 
Key Word From UniProt
 Aminoacyl-tRNAsynthetase; ATP-binding; Completeproteome; Cytoplasm; Ligase; Nucleotide-binding; Proteinbiosynthesis
Protein Sequence
 MSWSILELIR NNPEVLKENL KRRFIDTSTV DKAVELDKKW RQTLQEVERL RHEHNLISSQ 60
 IPKAPKEQKS ELINKAKELL KTLEDKEKEL QKIEEERENL LLSLPNLVHD SVPIGPDESY 120
 SVPIRFWGKF KVYKDDVNEF LKQTNGHKVD YEVINWKPVG HADMLENVLR LGDTKKAGEV 180
 AASRFYYLFN DIVWLDLALL LYAIDTITSR GYTLVLPPYM LRGEVIKSVI DLDTFKDAIY 240
 KIEGEDLYLI ATAEHSIAAL YYKEEIPKEE LPLKLVGVSP AFRKEAGAAN KDLKGIFRVH 300
 QFHKVEQFIF SSPEDSWKYH EEMIENAEEI FRGLGLPYRV INIASGDLGA PAAKKYDLEV 360
 WMPAQAKFRE MVSCSNCLDW QAYRMRIRYV EKNNKKGYLH TLNSTAIAST RAITAILENF 420
 QKEDGVVEVP KVLRKYLETF SGAPKEYIYP KKKPNTTS 458
  GO:0005737   C:cytoplasm IEA:UniProtKB-SubCell
  GO:0005524   F:ATP binding IEA:UniProtKB-HAMAP
  GO:0004828   F:serine-tRNA ligase activity IEA:UniProtKB-HAMAP
  GO:0016260   P:selenocysteine biosynthetic process IEA:UniProtKB-HAMAP
  GO:0097056   P:selenocysteinyl-tRNA(Sec) biosynthetic process IEA:UniProtKB-UniPathway
  GO:0006434   P:seryl-tRNA aminoacylation IEA:UniProtKB-HAMAP
  IPR002314   aa-tRNA-synt_IIb_cons-dom.
  IPR006195   aa-tRNA-synth_II.
  IPR002317   Ser-tRNA-ligase_type_1.
  IPR015866   Ser-tRNA-synth_1_N.
  IPR010978   tRNA-bd_arm.
  PF02403   Seryl_tRNA_N.
  PF00587   tRNA-synt_2b.
  PS50862   AA_TRNA_LIGASE_II.
  PR00981   TRNASYNTHSER.