| Tag | Content |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Anthrax toxin expression trans-acting positive regulator |
Protein Synonyms/Alias | |
Gene Name | atxA |
Gene Synonyms/Alias | pXO1-119, BXA0146, GBAA_pXO1_0146 |
Created Date | 3-June-2014 |
Organism | Bacillus anthracis |
NCBI Taxa ID | 1392 |
Phosphorylation | Position | Peptide | Code | Type | References | | 199 | QMYTYSKHKLCVLFA | H | LTP | [1] | | 379 | EISLLTMHFETQRML | H | LTP | [1] | |
Reference | [1]Opposing effects of histidine phosphorylation regulate the AtxA virulence transcription factor in Bacillus anthracis. Tsvetanova B,Wilson AC,Bongiorni C,Chiang C,Hoch JA,Perego M Mol. Microbiol. 2007, Feb;63(3):644-55. [ PMID:17302798] |
Functional Description From UniProt | FUNCTION: Acts in trans to stimulate anthrax toxins expression. It activates the transcription of the pagA, cya and lef genes. It also activates capB, a gene required for capsule production |
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| Activator; Capsulebiogenesis/degradation; Completeproteome; Plasmid; Referenceproteome; Repeat; Transcription; Transcriptionregulation; Virulence |
Protein Sequence | MLTPISIEKE HIRLINLLHF INEQNRWFTI KELSDYLQVA DKTVRKYLKL LEDEIPPSWN 60
LLVQKGKGIY LKKPLNESLS FVESKILRKS LNLQICEELV FKKNSMQSLA QKLHLQVGAL 120
YPIINQINYD IQSSHLNIKK KPLEISGREQ DVRVFMLRLY CNIPNDYWPF PYINKQNITD 180
LINKMEKILN VQMYTYSKHK LCVLFAITIS RLLSGNTIDN VSGLILVNKN DDHYKTVASI 240
TSELQNSFGV TLHETEISFL ALALLLSLGN SITTDSNKTL TSYKKTIMPL AKEITKGIEH 300
KLQLGINYDE SFLTYVVLII KKALDKNFIQ YYNYNIKFIR HIKQRHPNTF NTIQECISNL 360
NYTVYSHFDC YEISLLTMHF ETQRMLFKNN PKKIYVYTSQ GCIHREYISA LLEKRYNGLI 420
KIVRNTIINL TNESLQDMEI DIIISNVNLP IKNIPIVQIS EFPTERDFHE IKKII 475 |
| GO:0009405 P:pathogenesis IEA:UniProtKB-KW GO:0006355 P:regulation of transcription, DNA-templated IEA:UniProtKB-KW GO:0006351 P:transcription, DNA-templated IEA:UniProtKB-KW |
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