※ Protein Information
Tag Content
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Acetoacetate metabolism regulatory protein AtoC
Protein Synonyms/Alias
 
Gene Name
 atoC
Gene Synonyms/Alias
 az; OrderedLocusNames=b2220, JW2214
Created Date
 3-June-2014
Organism
 Escherichia coli (strain K12)
NCBI Taxa ID
 83333
Phosphorylation
Position
Peptide
Code
Type
References
55 HPDVVLMDIRMPEMD D LTP [1]
73 ALKEMRSHETRTPVI H LTP [1]
Reference
 [1]Phosphorylation activity of the response regulator of the two-component signal transduction system AtoS-AtoC in E. coli.
 Lioliou EE,Mimitou EP,Grigoroudis AI,Panagiotidis CH,Panagiotidis CA,Kyriakidis DA
 Biochim. Biophys. Acta 2005, Oct, 10;1725(3):257-68. [PMID:16153782]
Functional Description From UniProt
 FUNCTION: Member of the two-component regulatory system AtoS/AtoC involved in the transcriptional regulation of the ato genes for acetoacetate metabolism. Also an inhibitor of polyamine biosynthesis
Sequence Annotation From UniProt
 MOD_RES 55 55 4-aspartylphosphate (By similarity)
Key Word From UniProt
 ATP-binding; Completeproteome; Cytoplasm; DNA-binding; Nucleotide-binding; Phosphoprotein; Referenceproteome; Repressor; Transcription; Transcriptionregulation; Two-componentregulatorysystem
Protein Sequence
 MTAINRILIV DDEDNVRRML STAFALQGFE THCANNGRTA LHLFADIHPD VVLMDIRMPE 60
 MDGIKALKEM RSHETRTPVI LMTAYAEVET AVEALRCGAF DYVIKPFDLD ELNLIVQRAL 120
 QLQSMKKEIR HLHQALSTSW QWGHILTNSP AMMDICKDTA KIALSQASVL ISGESGTGKE 180
 LIARAIHYNS RRAKGPFIKV NCAALPESLL ESELFGHEKG AFTGAQTLRQ GLFERANEGT 240
 LLLDEIGEMP LVLQAKLLRI LQEREFERIG GHQTIKVDIR IIAATNRDLQ AMVKEGTFRE 300
 DLFYRLNVIH LILPPLRDRR EDISLLANHF LQKFSSENQR DIIDIDPMAM SLLTAWSWPG 360
 NIRELSNVIE RAVVMNSGPI IFSEDLPPQI RQPVCNAGEV KTAPVGERNL KEEIKRVEKR 420
 IIMEVLEQQE GNRTRTALML GISRRALMYK LQEYGIDPAD V 461
  GO:0005737   C:cytoplasm IEA:UniProtKB-SubCell
  GO:0005524   F:ATP binding IEA:UniProtKB-KW
  GO:0017111   F:nucleoside-triphosphatase activity IEA:InterPro
  GO:0000156   F:phosphorelay response regulator activity IEA:InterPro
  GO:0043565   F:sequence-specific DNA binding IEA:InterPro
  GO:0003700   F:sequence-specific DNA binding transcription factor activity IDA:EcoCyc
  GO:0045893   P:positive regulation of transcription, DNA-templated IDA:EcoCyc
  GO:0006351   P:transcription, DNA-templated IEA:UniProtKB-KW
  IPR003593   AAA+_ATPase.
  IPR011006   CheY-like_superfamily.
  IPR009057   Homeodomain-like.
  IPR002197   HTH_Fis.
  IPR027417   P-loop_NTPase.
  IPR001789   Sig_transdc_resp-reg_receiver.
  IPR002078   Sigma_54_int.
  IPR025662   Sigma_54_int_dom_ATP-bd_1.
  IPR025943   Sigma_54_int_dom_ATP-bd_2.
  IPR025944   Sigma_54_int_dom_CS.
  PF02954   HTH_8.
  PF00072   Response_reg.
  PF00158   Sigma54_activat.
  SM00382   AAA.
  SM00448   REC.
  PS50110   RESPONSE_REGULATORY.
  PS00675   SIGMA54_INTERACT_1.
  PS00676   SIGMA54_INTERACT_2.
  PS00688   SIGMA54_INTERACT_3.
  PS50045   SIGMA54_INTERACT_4.
  PR01590   HTHFIS.