※ Protein Information
Tag Content
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 UTP--glucose-1-phosphate uridylyltransferase
Protein Synonyms/Alias
 GSP33;  UDPGP
Gene Name
 gtaB
Gene Synonyms/Alias
 BSU35670
Created Date
 3-June-2014
Organism
 Bacillus subtilis (strain 168)
NCBI Taxa ID
 224308
Phosphorylation
Position
Peptide
Code
Type
References
76 DYSPELERNLEEKGK R HTP [1]
Reference
 [1]Global impact of protein arginine phosphorylation on the physiology of Bacillus subtilis.
 Elsholz AK,Turgay K,Michalik S,Hessling B,Gronau K,Oertel D,Mäder U,Bernhardt J,Becher D,Hecker M,Gerth U
 Proc. Natl. Acad. Sci. U.S.A. 2012, May, 8;109(19):7451-6. [PMID:22517742]
Functional Description From UniProt
 FUNCTION: Catalyzes the formation of UDP-glucose from glucose-1- phosphate and UTP. This is an intermediate step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i.e. the predominant glycolipid found in B.subtilis membrane, which is also used as a membrane anchor for lipoteichoic acid (LTA). Has a role in the biosynthesis of all phosphate-containing envelope polymers, since UDP-glucose serves as a glucosyl donor not only for the biosynthesis of LTA but also for wall teichoic acids (WTAs). Is required for biofilm formation. This is likely due to another role of UDP-glucose, which might also act as a metabolic signal regulating biofilm formation or may be involved in some unknown biosynthetic pathway essential for biofilm formation, e.g. the synthesis of an exopolysaccharide
Sequence Annotation From UniProt
 
Key Word From UniProt
 Carbohydratemetabolism; Completeproteome; Directproteinsequencing; Nucleotidyltransferase; Referenceproteome; Stressresponse; Transferase
Protein Sequence
 MKKVRKAIIP AAGLGTRFLP ATKAMPKEML PIVDKPTIQY IIEEAVEAGI EDIIIVTGKS 60
 KRAIEDHFDY SPELERNLEE KGKTELLEKV KKASNLADIH YIRQKEPKGL GHAVWCARNF 120
 IGDEPFAVLL GDDIVQAETP GLRQLMDEYE KTLSSIIGVQ QVPEEETHRY GIIDPLTSEG 180
 RRYQVKNFVE KPPKGTAPSN LAILGRYVFT PEIFMYLEEQ QVGAGGEIQL TDAIQKLNEI 240
 QRVFAYDFEG KRYDVGEKLG FITTTLEFAM QDKELRDQLV PFMEGLLNKE EI 292
  GO:0003983   F:UTP:glucose-1-phosphate uridylyltransferase activity IEA:UniProtKB-EC
  GO:0009246   P:enterobacterial common antigen biosynthetic process IEA:UniProtKB-UniPathway
  GO:0006950   P:response to stress IEA:UniProtKB-KW
  GO:0006011   P:UDP-glucose metabolic process IEA:InterPro
  IPR005771   GalU_uridylyltTrfase_bac/arc.
  IPR005835   NTP_transferase.
  PF00483   NTP_transferase.