| Tag | Content |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Translation initiation factor IF-2 |
Protein Synonyms/Alias | |
Gene Name | infB |
Gene Synonyms/Alias | SPD_0482 |
Created Date | 3-June-2014 |
Organism | Streptococcus pneumoniae serotype 2 (strain D39 / NCTC 7466) |
NCBI Taxa ID | 373153 |
Phosphorylation | Position | Peptide | Code | Type | References | | 529 | TIEAINHSKAANVPI | S | HTP | [1] | | 605 | QELKADPTVRAIGTV | T | HTP | [1] | | 522 | DDGVMPQTIEAINHS | T | HTP | [1] | |
Reference | [1]Phosphoproteomic analysis reveals the multiple roles of phosphorylation in pathogenic bacterium Streptococcus pneumoniae. Sun X,Ge F,Xiao CL,Yin XF,Ge R,Zhang LH,He QY J. Proteome Res. 2010, Jan;9(1):275-82. [ PMID:19894762] |
Functional Description From UniProt | FUNCTION: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity) |
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| Completeproteome; Cytoplasm; GTP-binding; Initiationfactor; Nucleotide-binding; Proteinbiosynthesis |
Protein Sequence | MSKKRLYEIA KELGKESKEV VARAKELGLD VKSHSSSVEE AVAAKIAASF KPAAAPKVEA 60
KPAAPKVSAE KKTEKSEPAK PAVAKEEAKP AEPVAPKTEK VAAKPQSRNF KAEREARAKE 120
QAERRKQNKG NNRDQQQNGN RQKNDGRNGG KQGQSNRDNR RFNDQAKKQQ GQQKRRNERR 180
QQEDKRSNQA APRIDFKARA AALKAEQNAE YARSSEERFK QYQAAKEALA QANKRKEPEE 240
IFEEAAKLAE QAQQVQAVVE VVPEKKEPAV DTRRKKQARP DKNRDDYDHE EDGPRKQQKN 300
RSSQNQVRNQ KNSNWNNNKK NKKGNNKNNR NQTPKPVTER KFHELPTEFE YTDGMTVAEI 360
AKRIKREPAE IVKKLFMMGV MATQNQSLDG ETIELLMVDY GIEAKQKVEV DNADIERFFV 420
EDGYLNEDEL VERPPVVTIM GHVDHGKTTL LDTLRNSRVA TGEAGGITQH IGAYQIVENG 480
KKITFLDTPG HAAFTSMRAR GASVTDITIL VVAADDGVMP QTIEAINHSK AANVPIIVAI 540
NKIDKPGANP ERVIGELAEH GVMSTAWGGD SEFVEISAKF NQNIEELLET VLLVAEIQEL 600
KADPTVRAIG TVIEARLDKG KGAVATLLVQ QGTLNVQDPI VVGNTFGRVR AMTNDLGRRV 660
KVAGPSTPVS ITGLNEAPMA GDHFAVYEDE KSARAAGEER AKRALMKQRQ ATQRVSLENL 720
FDTLKAGELK SVNVIIKADV QGSVEALSAS LQKIDVEGVK VTIVHSAVGA INESDVTLAE 780
ASNAFIVGFN VRPTPQARQQ AEADDVEIRL HSIIYKVIEE MEEAMKGMLD PEFEEKVIGE 840
AVIRETFKVS KVGTIGGFMV INGKVARDSK VRVIRDGVVI YDGELASLKH YKDDVKEVTN 900
GREGGLMIDG YNDIKMDDVI EAYVMEEIKR 930 |
| GO:0005737 C:cytoplasm IEA:UniProtKB-SubCell GO:0005525 F:GTP binding IEA:UniProtKB-KW GO:0003924 F:GTPase activity IEA:UniProtKB-HAMAP GO:0003743 F:translation initiation factor activity IEA:UniProtKB-HAMAP |
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