UniProt Accession

 DEF_STRP2;  Q04JP7

Genbank Protein ID

 CP000410

Genbank Nucleotide ID

 ABJ54406.1

Protein Name

 Peptide deformylase

Protein Synonyms/Alias

 PDF

Gene Name

 def

Gene Synonyms/Alias

 SPD_1285

Created Date

 3-June-2014

Organism

 Streptococcus pneumoniae serotype 2 (strain D39 / NCTC 7466)

NCBI Taxa ID

 373153

Phosphorylation

Reference

 [1]Phosphoproteomic analysis reveals the multiple roles of phosphorylation in pathogenic bacterium Streptococcus pneumoniae.
 Sun X,Ge F,Xiao CL,Yin XF,Ge R,Zhang LH,He QY
 J. Proteome Res. 2010, Jan;9(1):275-82. [PMID:19894762]

Functional Description From UniProt

 FUNCTION: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)

Sequence Annotation From UniProt

 

Key Word From UniProt

 Completeproteome; Hydrolase; Iron; Metal-binding; Proteinbiosynthesis

Protein Sequence

  GO:0005506   F:iron ion binding IEA:InterPro
  GO:0042586   F:peptide deformylase activity IEA:UniProtKB-HAMAP
  GO:0006412   P:translation IEA:UniProtKB-HAMAP

  IPR000181   Fmet_deformylase.
  IPR023635   Peptide_deformylase.

  PF01327   Pep_deformylase.

  PR01576   PDEFORMYLASE.