UniProt Accession

 CLPP1_MYCTO;  P9WPC4;  L0TBA3;  O53188;  P0A526

Genbank Protein ID

 AE000516

Genbank Nucleotide ID

 AAK46836.1

Protein Name

 ATP-dependent Clp protease proteolytic subunit 1

Protein Synonyms/Alias

 

Gene Name

 clpP1

Gene Synonyms/Alias

 clpP; OrderedLocusNames=MT2536

Created Date

 3-June-2014

Organism

 Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)

NCBI Taxa ID

 83331

Phosphorylation

Reference

 [1]Extensive phosphorylation with overlapping specificity by Mycobacterium tuberculosis serine/threonine protein kinases.
 Prisic S,Dankwa S,Schwartz D,Chou MF,Locasale JW,Kang CM,Bemis G,Church GM,Steen H,Husson RN
 Proc. Natl. Acad. Sci. U.S.A. 2010, Apr, 20;107(16):7521-6. [PMID:20368441]

Functional Description From UniProt

 FUNCTION: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)

Sequence Annotation From UniProt

 

Key Word From UniProt

 Completeproteome; Cytoplasm; Hydrolase; Protease; Serineprotease.

Protein Sequence

  IPR001907   ClpP.
  IPR023562   ClpP/TepA.
  IPR018215   ClpP_AS.

  PF00574   CLP_protease.

  PS00382   CLP_PROTEASE_HIS.

  PR00127   CLPPROTEASEP.