※ Protein Information
Tag Content
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Adenylate kinase
Protein Synonyms/Alias
 AK
Gene Name
 adk
Gene Synonyms/Alias
 MT0757
Created Date
 3-June-2014
Organism
 Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
NCBI Taxa ID
 83331
Phosphorylation
Position
Peptide
Code
Type
References
30 KLGIPQISTGELFRR S HTP [1]
Reference
 [1]Extensive phosphorylation with overlapping specificity by Mycobacterium tuberculosis serine/threonine protein kinases.
 Prisic S,Dankwa S,Schwartz D,Chou MF,Locasale JW,Kang CM,Bemis G,Church GM,Steen H,Husson RN
 Proc. Natl. Acad. Sci. U.S.A. 2010, Apr, 20;107(16):7521-6. [PMID:20368441]
Functional Description From UniProt
 FUNCTION: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism Has a broad specificity for nucleoside triphosphates, being highly active with ATP or dATP as phosphate donors, and less active with GTP or UTP (By similarity)
Sequence Annotation From UniProt
 
Key Word From UniProt
 ATP-binding; Completeproteome; Cytoplasm; Kinase; Nucleotidebiosynthesis; Nucleotide-binding; Transferase
Protein Sequence
 MRVLLLGPPG AGKGTQAVKL AEKLGIPQIS TGELFRRNIE EGTKLGVEAK RYLDAGDLVP 60
 SDLTNELVDD RLNNPDAANG FILDGYPRSV EQAKALHEML ERRGTDIDAV LEFRVSEEVL 120
 LERLKGRGRA DDTDDVILNR MKVYRDETAP LLEYYRDQLK TVDAVGTMDE VFARALRALG 180
 K 181
  IPR000850   Adenylat/UMP-CMP_kin.
  IPR027417   P-loop_NTPase.
  PS00113   ADENYLATE_KINASE.
  PR00094   ADENYLTKNASE.