| Tag | Content |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Penicillin-binding protein A |
Protein Synonyms/Alias | PBPA |
Gene Name | pbpA |
Gene Synonyms/Alias | MT0019 |
Created Date | 3-June-2014 |
Organism | Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) |
NCBI Taxa ID | 83331 |
Phosphorylation | Position | Peptide | Code | Type | References | | 437 | HGTDPRHTPPHAWYI | T | LTP | [1] | | 362 | TIANGGITMRPYLVG | T | LTP | [1] | |
Reference | [1]The serine/threonine kinase PknB of Mycobacterium tuberculosis phosphorylates PBPA, a penicillin-binding protein required for cell division. Dasgupta A,Datta P,Kundu M,Basu J Microbiology (Reading, Engl.) 2006, Feb;152(Pt 2):493-504. [ PMID:16436437] |
Functional Description From UniProt | FUNCTION: Cell wall formation. Plays an important role in cell division and cell shape maintenance by cross-linking adjacent peptidoglycan chains through transpeptidation (By similarity) |
| TRANSMEM 8 28 Helical; Signal-anchor for type II
MOD_RES 362 362 Phosphothreonine; by PknB (By similarity)
MOD_RES 437 437 Phosphothreonine; by PknB (By similarity) |
| Cellmembrane; Cellshape; Cellwallbiogenesis/degradation; Completeproteome; Membrane; Peptidoglycansynthesis; Phosphoprotein; Signal-anchor; Transferase; Transmembrane; Transmembranehelix |
Protein Sequence | MNASLRRISV TVMALIVLLL LNATMTQVFT ADGLRADPRN QRVLLDEYSR QRGQITAGGQ 60
LLAYSVATDG RFRFLRVYPN PEVYAPVTGF YSLRYSSTAL ERAEDPILNG SDRRLFGRRL 120
ADFFTGRDPR GGNVDTTINP RIQQAGWDAM QQGCYGPCKG AVVALEPSTG KILALVSSPS 180
YDPNLLASHN PEVQAQAWQR LGDNPASPLT NRAISETYPP GSTFKVITTA AALAAGATET 240
EQLTAAPTIP LPGSTAQLEN YGGAPCGDEP TVSLREAFVK SCNTAFVQLG IRTGADALRS 300
MARAFGLDSP PRPTPLQVAE STVGPIPDSA ALGMTSIGQK DVALTPLANA EIAATIANGG 360
ITMRPYLVGS LKGPDLANIS TTVGYQQRRA VSPQVAAKLT ELMVGAEKVA QQKGAIPGVQ 420
IASKTGTAEH GTDPRHTPPH AWYIAFAPAQ APKVAVAVLV ENGADRLSAT GGALAAPIGR 480
AVIEAALQGE P 491 |
| |
| |
| |
| |
| |
| |
