※ Protein Information
Tag Content
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Anti-sigma factor RshA
Protein Synonyms/Alias
 
Gene Name
 rshA
Gene Synonyms/Alias
 MT3318
Created Date
 3-June-2014
Organism
 Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
NCBI Taxa ID
 83331
Phosphorylation
Position
Peptide
Code
Type
References
94 LRLEIRRTTIIRGGP T LTP [1]
Reference
 [1]Regulation of the SigH stress response regulon by an essential protein kinase in Mycobacterium tuberculosis.
 Park ST,Kang CM,Husson RN
 Proc. Natl. Acad. Sci. U.S.A. 2008, Sep, 2;105(35):13105-10. [PMID:18728196]
Functional Description From UniProt
 FUNCTION: An redox-regulated anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigH. ECF sigma factors are held in an inactive form by a cognate anti-sigma factor. RshA and some peptides derived from it inhibit the sigma factor activity of SigH. Probably releases SigH during oxidative stress (By similarity)
Sequence Annotation From UniProt
 MOD_RES 94 94 Phosphothreonine (By similarity)
Key Word From UniProt
 Completeproteome; Iron; Iron-sulfur; Metal-binding; Phosphoprotein; Stressresponse; Transcription; Transcriptionregulation
Protein Sequence
 MSENCGPTDA HADHDDSHGG MGCAEVIAEV WTLLDGECTP ETRERLRRHL EACPGCLRHY 60
 GLEERIKALI GTKCRGDRAP EGLRERLRLE IRRTTIIRGG P 101
  IPR024020   Anit_sigma_micothiol_RsrA.
  IPR014295   Anti-sigma.
  IPR027383   Znf_put.
  PF13490   zf-HC2.