| Tag | Content |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Sensor histidine kinase MtrB |
Protein Synonyms/Alias | |
Gene Name | mtrB |
Gene Synonyms/Alias | MT3343 |
Created Date | 3-June-2014 |
Organism | Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) |
NCBI Taxa ID | 83331 |
Phosphorylation | Position | Peptide | Code | Type | References | | 217 | LVRGTMATGGLVLLV | T | HTP | [1] | | 234 | AGIALLVSRQVVVPV | S | HTP | [1] | | 214 | TITLVRGTMATGGLV | T | HTP | [1] | |
Reference | [1]Extensive phosphorylation with overlapping specificity by Mycobacterium tuberculosis serine/threonine protein kinases. Prisic S,Dankwa S,Schwartz D,Chou MF,Locasale JW,Kang CM,Bemis G,Church GM,Steen H,Husson RN Proc. Natl. Acad. Sci. U.S.A. 2010, Apr, 20;107(16):7521-6. [ PMID:20368441] |
Functional Description From UniProt | FUNCTION: Member of the two-component regulatory system MtrA/MtrB Probably functions as a membrane-associated protein kinase that phosphorylates MtrA in response to environmental signals. Probably plays a role in cell division (By similarity) |
| TRANSMEM 42 62 Helical; (Potential)
TRANSMEM 213 233 Helical; (Potential)
MOD_RES 305 305 Phosphohistidine; by autocatalysis (By similarity) |
| ATP-binding; Cellmembrane; Completeproteome; Kinase; Membrane; Nucleotide-binding; Phosphoprotein; Transferase; Transmembrane; Transmembranehelix; Two-componentregulatorysystem |
Protein Sequence | MIFGSRRRIR GRRGRSGPMT RGLSALSRAV AVAWRRSLQL RVVALTLGLS LAVILALGFV 60
LTSQVTNRVL DIKVRAAIDQ IERARTTVSG IVNGEETRSL DSSLQLARNT LTSKTDPASG 120
AGLAGAFDAV LMVPGDGPRA ASTAGPVDQV PNALRGFVKA GQAAYQYATV QTEGFSGPAL 180
IIGTPTLSRV ANLELYLIFP LASEQATITL VRGTMATGGL VLLVLLAGIA LLVSRQVVVP 240
VRSASRIAER FAEGHLSERM PVRGEDDMAR LAVSFNDMAE SLSRQIAQLE EFGNLQRRFT 300
SDVSHELRTP LTTVRMAADL IYDHSADLDP TLRRSTELMV SELDRFETLL NDLLEISRHD 360
AGVAELSVEA VDLRTTVNNA LGNVGHLAEE AGIELLVDLP AEQVIAEVDA RRVERILRNL 420
IANAIDHAEH KPVRIRMAAD EDTVAVTVRD YGVGLRPGEE KLVFSRFWRS DPSRVRRSGG 480
TGLGLAISVE DARLHQGRLE AWGEPGEGAC FRLTLPLVRG HKVTTSPLPM KPIPQPVLQP 540
VAQPNPQPMP PEYKERQRPR EHAEWSG 567 |
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