| Tag | Content |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Phosphoribosylglycinamide formyltransferase 2 PurT |
Protein Synonyms/Alias | |
Gene Name | purT |
Gene Synonyms/Alias | Rv0389; ORFNames=RVBD_0389 |
Created Date | 3-June-2014 |
Organism | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) |
NCBI Taxa ID | 83332 |
Phosphorylation | Position | Peptide | Code | Type | References | | 206 | GHQVQPQTGGVSPRV | T | HTP | [1] | |
Reference | [1]Extensive phosphorylation with overlapping specificity by Mycobacterium tuberculosis serine/threonine protein kinases. Prisic S,Dankwa S,Schwartz D,Chou MF,Locasale JW,Kang CM,Bemis G,Church GM,Steen H,Husson RN Proc. Natl. Acad. Sci. U.S.A. 2010, Apr, 20;107(16):7521-6. [ PMID:20368441] |
Functional Description From UniProt | FUNCTION: Catalyzes two reactions: the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR; the second, a side reaction, is the production of acetyl phosphate and ADP from acetate and ATP (By similarity) |
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| ATP-binding; Completeproteome; Metal-binding; Nucleotide-binding; Purinebiosynthesis; Referenceproteome; Transferase |
Protein Sequence | MIDGWTEEQH EPTVRHERPA APQDVRRVML LGSAEPSREL AIALQGLGAE VIAVDGYVGA 60
PAHRIADQSV VVTMTDAEEL TAVIRRLQPD FLVTVTAAVS VDALDAVEQA DGECTELVPN 120
ARAVRCTADR EGLRRLAADQ LGLPTAPFWF VGSLGELQAV AVHAGFPLLV SPVAGVAGQG 180
SSVVAGPNEV EPAWQRAAGH QVQPQTGGVS PRVCAESVVE IEFLVTMIVV CSQGPNGPLI 240
EFCAPIGHRD ADAGELESWQ PQKLSTAALD AAKSIAARIV KALGGRGVFG VELMINGDEV 300
YFADVTVCPA GSAWVTVRSQ RLSVFELQAR AILGLAVDTL MISPGAARVI NPDHTAGRAA 360
VGAAPPADAL TGALGVPESD VVIFGRGLGV ALATAPEVAI ARERAREVAS RLNVPDSRE 419 |
| GO:0005829 C:cytosol IDA:MTBBASE GO:0005524 F:ATP binding IEA:UniProtKB-KW GO:0000287 F:magnesium ion binding IEA:InterPro GO:0004644 F:phosphoribosylglycinamide formyltransferase activity IEA:InterPro GO:0006189 P:'de novo' IMP biosynthetic process IEA:UniProtKB-UniPathway |
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