※ Protein Information
Tag Content
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 ATP-dependent Clp protease proteolytic subunit
Protein Synonyms/Alias
 
Gene Name
 clpP
Gene Synonyms/Alias
 yvdN; OrderedLocusNames=BSU34540
Created Date
 3-June-2014
Organism
 Bacillus subtilis (strain 168)
NCBI Taxa ID
 224308
Phosphorylation
Position
Peptide
Code
Type
References
13 TVIEQTNRGERAYDI R HTP [1]
11 IPTVIEQTNRGERAY T HTP [1]
16 EQTNRGERAYDIYSR R HTP [1]
Reference
 [1]Global impact of protein arginine phosphorylation on the physiology of Bacillus subtilis.
 Elsholz AK,Turgay K,Michalik S,Hessling B,Gronau K,Oertel D,Mäder U,Bernhardt J,Becher D,Hecker M,Gerth U
 Proc. Natl. Acad. Sci. U.S.A. 2012, May, 8;109(19):7451-6. [PMID:22517742]
Functional Description From UniProt
 FUNCTION: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity). ClpXP is involved in the complete degradation of the Site-2 clipped anti-sigma-W factor RsiW. This results in the release of SigW and the transcription activation of the genes under the control of the sigma-W factor
Sequence Annotation From UniProt
 
Key Word From UniProt
 3D-structure; Completeproteome; Cytoplasm; Directproteinsequencing; Hydrolase; Protease; Referenceproteome; Serineprotease; Stressresponse
Protein Sequence
 MNLIPTVIEQ TNRGERAYDI YSRLLKDRII MLGSAIDDNV ANSIVSQLLF LAAEDPEKEI 60
 SLYINSPGGS ITAGMAIYDT MQFIKPKVST ICIGMAASMG AFLLAAGEKG KRYALPNSEV 120
 MIHQPLGGAQ GQATEIEIAA KRILLLRDKL NKVLAERTGQ PLEVIERDTD RDNFKSAEEA 180
 LEYGLIDKIL THTEDKK 197
  GO:0005737   C:cytoplasm IEA:UniProtKB-SubCell
  GO:0005524   F:ATP binding IEA:UniProtKB-KW
  GO:0004176   F:ATP-dependent peptidase activity IMP:CACAO
  GO:0004252   F:serine-type endopeptidase activity IEA:UniProtKB-HAMAP
  GO:0006200   P:ATP catabolic process IMP:GOC
  GO:0006950   P:response to stress IEA:UniProtKB-KW
  IPR001907   ClpP.
  IPR023562   ClpP/TepA.
  IPR018215   ClpP_AS.
  PF00574   CLP_protease.
  PS00382   CLP_PROTEASE_HIS.
  PS00381   CLP_PROTEASE_SER.
  PR00127   CLPPROTEASEP.