| Tag | Content |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Ribonucleoside-diphosphate reductase subunit alpha |
Protein Synonyms/Alias | |
Gene Name | nrdE |
Gene Synonyms/Alias | MPN_324; ORFNames=MP512 |
Created Date | 3-June-2014 |
Organism | Mycoplasma pneumoniae (strain ATCC 29342 / M129) |
NCBI Taxa ID | 272634 |
Phosphorylation | Position | Peptide | Code | Type | References | | 159 | TNRFQPATPTFLNAG | T | HTP | [1] | | 412 | KKVGNDISCNLGSLN | S | HTP | [1] | |
Reference | [1]The phosphoproteome of the minimal bacterium Mycoplasma pneumoniae: analysis of the complete known Ser/Thr kinome suggests the existence of novel kinases. Schmidl SR,Gronau K,Pietack N,Hecker M,Becher D,Stülke J Mol. Cell Proteomics 2010, Jun;9(6):1228-42. [ PMID:20097688] |
Functional Description From UniProt | FUNCTION: Provides the precursors necessary for DNA synthesis Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) |
| DISULFID 176 413 Redox-active (By similarity) |
| Allostericenzyme; ATP-binding; Completeproteome; Disulfidebond; DNAreplication; Nucleotide-binding; Oxidoreductase; Referenceproteome |
Protein Sequence | MSVKEKIPAF NTQEDLESYI SLNAYTKVYG DFKMDLHAVE AYIQEHVKPK TKVFHSTKER 60
LDFLVKNDYY DENIINMYSF EQFEEITRKA YAYRFRYANF MGAFKFYNAY ALKTFDGKWY 120
LENYEDRVVM NVLFLANGNY NKALKLLKQI ITNRFQPATP TFLNAGRKKR GEFVSCYLLR 180
IEDNMESIGR AITTTLQLSK RDGGVALLLT NIRESGAPIK KIENQSSGII PIMKLLEDSF 240
SYANQLGQRQ GAGAVYLHAH HPDVMQFLDT KRENADEKIR IKSLSLGLVI PDITFTLAKN 300
NEEMALFSPY DVYEEYGKPL SDISVTEMYY ELLANQRIKK TFINARKFFQ TVAELHFESG 360
YPYILFDDTV NRRNAHPNRI VMSNLCSEIV QPSTPSEFHH DLAFKKVGND ISCNLGSLNI 420
AKAMESGPEF SELVKLAIES LDLVSRVSNL ETAPSIQKGN SENHALGLGA MNLHGFLATN 480
QIYYNSPEAI DFTNIFFYTV AYHAFKASSE LALEKGKFKN FENTKFADGS YFDKYIKVEP 540
DFWTPKTERV KALFQKYQVE IPTRENWKEL ALNIQKNGLA NSHLLAIAPT GSISYLSSCT 600
PSLQPVVSPV EVRKEGRLGR IYVPAYQLNK DSYPFYKDGA YELGPEPIIN IAAAAQQHVD 660
QAISLTLFMT DKATTRDLNK AYIYAFKKGC SSIYYVRVRQ EVLEDSEDHT IQMQQCEACV 720
I 721 |
| GO:0005971 C:ribonucleoside-diphosphate reductase complex IEA:InterPro GO:0005524 F:ATP binding IEA:UniProtKB-KW GO:0004748 F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor IEA:UniProtKB-EC GO:0006260 P:DNA replication IEA:UniProtKB-UniPathway |
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