| Tag | Content |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | tRNA (cmo5U34)-methyltransferase |
Protein Synonyms/Alias | |
Gene Name | cmoA |
Gene Synonyms/Alias | yecO; OrderedLocusNames=b1870, JW1859 |
Created Date | 3-June-2014 |
Organism | Escherichia coli (strain K12) |
NCBI Taxa ID | 83333 |
Phosphorylation | Position | Peptide | Code | Type | References | | 6 | **MSHRDTLFSAPIA | T | HTP | [1] | | 2 | ******MSHRDTLFS | S | HTP | [1] | |
Reference | [1]Phosphoproteome analysis of E. coli reveals evolutionary conservation of bacterial Ser/Thr/Tyr phosphorylation. Macek B,Gnad F,Soufi B,Kumar C,Olsen JV,Mijakovic I,Mann M Mol. Cell Proteomics 2008, Feb;7(2):299-307. [ PMID:17938405] |
Functional Description From UniProt | FUNCTION: Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity) |
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| 3D-structure; Completeproteome; Methyltransferase; Referenceproteome; S-adenosyl-L-methionine; Transferase; tRNAprocessing |
Protein Sequence | MSHRDTLFSA PIARLGDWTF DERVAEVFPD MIQRSVPGYS NIISMIGMLA ERFVQPGTQV 60
YDLGCSLGAA TLSVRRNIHH DNCKIIAIDN SPAMIERCRR HIDAYKAPTP VDVIEGDIRD 120
IAIENASMVV LNFTLQFLEP SERQALLDKI YQGLNPGGAL VLSEKFSFED AKVGELLFNM 180
HHDFKRANGY SELEISQKRS MLENVMLTDS VETHKARLHN AGFEHSELWF QCFNFGSLVA 240
LKAEDAA 247 |
| GO:0008757 F:S-adenosylmethionine-dependent methyltransferase activity IEA:UniProtKB-HAMAP GO:0016300 F:tRNA (uracil) methyltransferase activity IEA:InterPro GO:0002098 P:tRNA wobble uridine modification IMP:EcoCyc |
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