※ Protein Information
Tag Content
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 PTS-dependent dihydroxyacetone kinase, ADP-binding subunit DhaL
Protein Synonyms/Alias
 
Gene Name
 dhaL
Gene Synonyms/Alias
 ycgS; OrderedLocusNames=b1199, JW5186
Created Date
 3-June-2014
Organism
 Escherichia coli (strain K12)
NCBI Taxa ID
 83333
Phosphorylation
Position
Peptide
Code
Type
References
38 REIGDADHGLNMNRG H LTP [1]
Reference
 [1]From ATP as substrate to ADP as coenzyme: functional evolution of the nucleotide binding subunit of dihydroxyacetone kinases.
 Bächler C,Flükiger-Brühwiler K,Schneider P,Bähler P,Erni B
 J. Biol. Chem. 2005, May, 6;280(18):18321-5. [PMID:15753087]
Functional Description From UniProt
 FUNCTION: ADP-binding subunit of the dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone. DhaL- ADP receives a phosphoryl group from DhaM and transmits it to dihydroxyacetone. DhaL-ADP acts also as a coactivator by binding to the sensor domain of DhaR. DhaL-ATP is inactive
Sequence Annotation From UniProt
 
Key Word From UniProt
 3D-structure; ATP-binding; Completeproteome; Glycerolmetabolism; Kinase; Nucleotide-binding; Referenceproteome; Transferase
Protein Sequence
 MSLSRTQIVN WLTRCGDIFS TESEYLTGLD REIGDADHGL NMNRGFSKVV EKLPAIADKD 60
 IGFILKNTGM TLLSSVGGAS GPLFGTFFIR AAQATQARQS LTLEELYQMF RDGADGVISR 120
 GKAEPGDKTM CDVWVPVVES LRQSSEQNLS VPVALEAASS IAESAAQSTI TMQARKGRAS 180
 YLGERSIGHQ DPGATSVMFM MQMLALAAKE 210
  GO:0043531   F:ADP binding IDA:EcoCyc
  GO:0005524   F:ATP binding IEA:UniProtKB-KW
  GO:0004371   F:glycerone kinase activity IEA:InterPro
  GO:0000287   F:magnesium ion binding IDA:EcoCyc
  GO:0019563   P:glycerol catabolic process IEA:UniProtKB-UniPathway
  IPR012737   DhaK_L_YcgS.
  IPR004007   DhaL_dom.
  PF02734   Dak2.
  PS51480   DHAL.