| Tag | Content |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Pyruvate dehydrogenase E1 component subunit alpha |
Protein Synonyms/Alias | |
Gene Name | pdhA |
Gene Synonyms/Alias | MPN_393; ORFNames=MP445 |
Created Date | 3-June-2014 |
Organism | Mycoplasma pneumoniae (strain ATCC 29342 / M129) |
NCBI Taxa ID | 272634 |
Phosphorylation | Position | Peptide | Code | Type | References | | 205 | STRTKLESAVSDLST | S | HTP | [1] | |
Reference | [1]The phosphoproteome of the minimal bacterium Mycoplasma pneumoniae: analysis of the complete known Ser/Thr kinome suggests the existence of novel kinases. Schmidl SR,Gronau K,Pietack N,Hecker M,Becher D,Stülke J Mol. Cell Proteomics 2010, Jun;9(6):1228-42. [ PMID:20097688] |
Functional Description From UniProt | FUNCTION: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity) |
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| Completeproteome; Glycolysis; Oxidoreductase; Pyruvate; Referenceproteome; Thiaminepyrophosphate |
Protein Sequence | MAILIKNKVP TTLYQVYDNE GKLMDPNHKI TLSNEQLKHA FYLMNLSRIM DKKMLVWQRA 60
GKMLNFAPNL GEEALQVGMG MGLNENDWFC PTFRSGALML YRGVKPEQLL LYWNGNENGS 120
KIEAKYKTLP INITIGAQYS HAAGLGYMLH YKKLPNVAVT MIGDGGTAEG EFYEAMNIAS 180
IHKWNSVFCI NNNQFAISTR TKLESAVSDL STKAIAVNIP RIRVDGNDLI ASYEAMHEAA 240
NYARSGNGPV LIEFFSWRQG PHTTSDDPSI YRTKEEEAEA MKSDPVKRLR NFLFDRGILT 300
PQQEEEMVAK IEQEVQAAYE VMVSKTPVTL DEVFDYNYEK LTPDLARQKA EAKKYFKD 358 |
| GO:0004739 F:pyruvate dehydrogenase (acetyl-transferring) activity IEA:UniProtKB-EC GO:0030976 F:thiamine pyrophosphate binding IEA:InterPro GO:0006096 P:glycolytic process IEA:UniProtKB-KW |
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