UniProt Accession

 CSRA_ECO57;  P69915;  P31803

Genbank Protein ID

 AE005174;  BA000007

Genbank Nucleotide ID

 AAG57800.1;  BAB36976.1

Protein Name

 Carbon storage regulator

Protein Synonyms/Alias

 

Gene Name

 csrA

Gene Synonyms/Alias

 zfiA; OrderedLocusNames=Z3998, ECs3553

Created Date

 3-June-2014

Organism

 Escherichia coli O157:H7

NCBI Taxa ID

 83334

Phosphorylation

Reference

 [1]The Escherichia coli phosphotyrosine proteome relates to core pathways and virulence.
 Hansen AM,Chaerkady R,Sharma J,Díaz-Mejía JJ,Tyagi N,Renuse S,Jacob HK,Pinto SM,Sahasrabuddhe NA,Kim MS,Delanghe B,Srinivasan N,Emili A,Kaper JB,Pandey A
 PLoS Pathog. 2013;9(6):e1003403. [PMID:23785281]

Functional Description From UniProt

 FUNCTION: Affects glycogen biosynthesis, gluconeogenesis, cell size and surface properties. Regulates glycogen synthesis under both aerobic and anaerobic conditions. Seems to accelerate the degradation of glg gene transcripts, potentially through selective RNA binding. Acts to inhibit interaction between the LetD protein and the A subunit of DNA gyrase. Also required for motility and flagellum biosynthesis through the post-transcriptional activation of flhDC expression. This involves binding to and stabilization of the flhDC message by CsrA (By similarity)

Sequence Annotation From UniProt

 

Key Word From UniProt

 Completeproteome; RNA-binding.

Protein Sequence

  GO:0003723   F:RNA binding IEA:UniProtKB-HAMAP
  GO:0006402   P:mRNA catabolic process IEA:UniProtKB-HAMAP
  GO:0006109   P:regulation of carbohydrate metabolic process IEA:UniProtKB-HAMAP

  IPR003751   CsrA.

  PF02599   CsrA.