UniProt Accession

 PTKA_ECOLI;  P69828;  P37187;  P76413;  P94757;  P97243

Genbank Protein ID

 X79837;  U00096;  AP009048;  AP009048

Genbank Nucleotide ID

 CAA56228.1;  AAC75155.1;  BAA15964.1;  BAA15957.2

Protein Name

 Galactitol-specific phosphotransferase enzyme IIA component

Protein Synonyms/Alias

 

Gene Name

 gatA

Gene Synonyms/Alias

 b2094, JW2078/JW2081

Created Date

 3-June-2014

Organism

 Escherichia coli (strain K12)

NCBI Taxa ID

 83333

Phosphorylation

Reference

 [1]Phosphoproteome analysis of E. coli reveals evolutionary conservation of bacterial Ser/Thr/Tyr phosphorylation.
 Macek B,Gnad F,Soufi B,Kumar C,Olsen JV,Mijakovic I,Mann M
 Mol. Cell Proteomics 2008, Feb;7(2):299-307. [PMID:17938405]
 [2]The Escherichia coli phosphotyrosine proteome relates to core pathways and virulence.
 Hansen AM,Chaerkady R,Sharma J,Díaz-Mejía JJ,Tyagi N,Renuse S,Jacob HK,Pinto SM,Sahasrabuddhe NA,Kim MS,Delanghe B,Srinivasan N,Emili A,Kaper JB,Pandey A
 PLoS Pathog. 2013;9(6):e1003403. [PMID:23785281]

Functional Description From UniProt

 FUNCTION: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in galactitol transport

Sequence Annotation From UniProt

 

Key Word From UniProt

 Completeproteome; Cytoplasm; Galactitolmetabolism; Kinase; Phosphotransferasesystem; Referenceproteome; Sugartransport; Transferase; Transport

Protein Sequence

  GO:0005737   C:cytoplasm IEA:UniProtKB-SubCell
  GO:0016301   F:kinase activity IEA:UniProtKB-KW
  GO:0005215   F:transporter activity IEA:InterPro
  GO:0019402   P:galactitol metabolic process IEA:UniProtKB-KW
  GO:0009401   P:phosphoenolpyruvate-dependent sugar phosphotransferase system IEA:UniProtKB-KW

  IPR016152   PTrfase/Anion_transptr.
  IPR002178   PTS_EIIA_type-2_dom.

  PF00359   PTS_EIIA_2.

  PS51094   PTS_EIIA_TYPE_2.