※ Protein Information
Tag Content
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Multiphosphoryl transfer protein
Protein Synonyms/Alias
 MTP;  Protein H
Gene Name
 fruB
Gene Synonyms/Alias
 fpr, fruF; OrderedLocusNames=b2169, JW2156
Created Date
 3-June-2014
Organism
 Escherichia coli (strain K12)
NCBI Taxa ID
 83333
Phosphorylation
Position
Peptide
Code
Type
References
50 MLAREQQTSTFLGNG T HTP [1]
51 LAREQQTSTFLGNGI S HTP [1]
5 ***MFQLSVQDIHPG S HTP [1]
64 GIAIPHGTTDTRDQV T HTP [1]
118 RQLTHVLSDDSVAEQ S HTP [1]
65 IAIPHGTTDTRDQVL T HTP [1]
121 THVLSDDSVAEQLKS S HTP [1]
52 AREQQTSTFLGNGIA T HTP [1]
Reference
 [1]Phosphoproteome analysis of E. coli reveals evolutionary conservation of bacterial Ser/Thr/Tyr phosphorylation.
 Macek B,Gnad F,Soufi B,Kumar C,Olsen JV,Mijakovic I,Mann M
 Mol. Cell Proteomics 2008, Feb;7(2):299-307. [PMID:17938405]
Functional Description From UniProt
 FUNCTION: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in fructose transport
Sequence Annotation From UniProt
 
Key Word From UniProt
 Completeproteome; Cytoplasm; Kinase; Phosphotransferasesystem; Referenceproteome; Sugartransport; Transferase; Transport
Protein Sequence
 MFQLSVQDIH PGEKAGDKEE AIRQVAAALV QAGNVAEGYV NGMLAREQQT STFLGNGIAI 60
 PHGTTDTRDQ VLKTGVQVFQ FPEGVTWGDG QVAYVAIGIA ASSDEHLGLL RQLTHVLSDD 120
 SVAEQLKSAT TAEELRALLM GEKQSEQLKL DNEMLTLDIV ASDLLTLQAL NAARLKEAGA 180
 VDATFVTKAI NEQPLNLGQG IWLSDSAEGN LRSAIAVSRA ANAFDVDGET AAMLVSVAMN 240
 DDQPIAVLKR LADLLLDNKA DRLLKADAAT LLALLTSDDA PTDDVLSAEF VVRNEHGLHA 300
 RPGTMLVNTI KQFNSDITVT NLDGTGKPAN GRSLMKVVAL GVKKGHRLRF TAQGADAEQA 360
 LKAIGDAIAA GLGEGA 376
  GO:0005737   C:cytoplasm IEA:UniProtKB-SubCell
  GO:0016301   F:kinase activity IEA:UniProtKB-KW
  GO:0005351   F:sugar:hydrogen symporter activity IEA:InterPro
  GO:0009401   P:phosphoenolpyruvate-dependent sugar phosphotransferase system IEA:UniProtKB-KW
  IPR000032   HPr_prot-like.
  IPR016152   PTrfase/Anion_transptr.
  IPR002178   PTS_EIIA_type-2_dom.
  IPR001020   PTS_HPr_His_P_site.
  IPR002114   PTS_HPr_Ser_P_site.
  PF00381   PTS-HPr.
  PF00359   PTS_EIIA_2.
  PS51094   PTS_EIIA_TYPE_2.
  PS00372   PTS_EIIA_TYPE_2_HIS.
  PS51350   PTS_HPR_DOM.
  PS00369   PTS_HPR_HIS.
  PS00589   PTS_HPR_SER.
  PR00107   PHOSPHOCPHPR.