※ Protein Information
Tag Content
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Glucose-specific phosphotransferase enzyme IIA component
Protein Synonyms/Alias
 
Gene Name
 crr
Gene Synonyms/Alias
 gsr, iex, tgs, treD
Created Date
 3-June-2014
Organism
 Escherichia coli (strain K12)
NCBI Taxa ID
 83333
Phosphorylation
Position
Peptide
Code
Type
References
154 IKELIKLSGSVTVGE S HTP [1]
156 ELIKLSGSVTVGETP S HTP [1]
12 DKLKSLVSDDKKDTG S HTP [2]
134 LLEEKAKSTLTPVVI S HTP [2]
91 SGVELFVHFGIDTVE H NA UniProt
Reference
 [1]Phosphoproteome analysis of E. coli reveals evolutionary conservation of bacterial Ser/Thr/Tyr phosphorylation.
 Macek B,Gnad F,Soufi B,Kumar C,Olsen JV,Mijakovic I,Mann M
 Mol. Cell Proteomics 2008, Feb;7(2):299-307. [PMID:17938405]
 [2]Global dynamics of the Escherichia coli proteome and phosphoproteome during growth in minimal medium.
 Soares NC,Spät P,Krug K,Macek B
 J. Proteome Res. 2013, Jun, 7;12(6):2611-21. [PMID:23590516]
Functional Description From UniProt
 FUNCTION: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in glucose transport
Sequence Annotation From UniProt
 
Key Word From UniProt
 3D-structure; Completeproteome; Cytoplasm; Directproteinsequencing; Kinase; Metal-binding; Phosphotransferasesystem; Referenceproteome; Sugartransport; Transferase; Transport; Zinc
Protein Sequence
 MGLFDKLKSL VSDDKKDTGT IEIIAPLSGE IVNIEDVPDV VFAEKIVGDG IAIKPTGNKM 60
 VAPVDGTIGK IFETNHAFSI ESDSGVELFV HFGIDTVELK GEGFKRIAEE GQRVKVGDTV 120
 IEFDLPLLEE KAKSTLTPVV ISNMDEIKEL IKLSGSVTVG ETPVIRIKK 169
  GO:0005829   C:cytosol IDA:UniProtKB
  GO:0031234   C:extrinsic component of cytoplasmic side of plasma membrane IDA:EcoCyc
  GO:0016020   C:membrane IDA:UniProtKB
  GO:0016301   F:kinase activity IDA:EcoCyc
  GO:0046872   F:metal ion binding IEA:UniProtKB-KW
  GO:0005351   F:sugar:hydrogen symporter activity IEA:InterPro
  GO:0009401   P:phosphoenolpyruvate-dependent sugar phosphotransferase system IDA:EcoCyc
  IPR011055   Dup_hybrid_motif.
  IPR001127   PTS_EIIA_1_perm.
  PF00358   PTS_EIIA_1.
  PS51093   PTS_EIIA_TYPE_1.
  PS00371   PTS_EIIA_TYPE_1_HIS.