※ Protein Information
Tag Content
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 50S ribosomal protein L22
Protein Synonyms/Alias
 
Gene Name
 rplV
Gene Synonyms/Alias
 eryB; OrderedLocusNames=b3315, JW3277
Created Date
 3-June-2014
Organism
 Escherichia coli (strain K12)
NCBI Taxa ID
 83333
Phosphorylation
Position
Peptide
Code
Type
References
39 ALDILTYTNKKAAVL T HTP [1]
101 DRILKRTSHITVVVS S HTP [1]
38 QALDILTYTNKKAAV Y HTP [1]
104 LKRTSHITVVVSDRM T HTP [1]
100 ADRILKRTSHITVVV T HTP [1]
37 SQALDILTYTNKKAA T HTP [1]
Reference
 [1]Comprehensive analysis of phosphorylated proteins of Escherichia coli ribosomes.
 Soung GY,Miller JL,Koc H,Koc EC
 J. Proteome Res. 2009, Jul;8(7):3390-402. [PMID:19469554]
Functional Description From UniProt
 FUNCTION: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20 It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome
Sequence Annotation From UniProt
 
Key Word From UniProt
 3D-structure; Antibioticresistance; Completeproteome; Directproteinsequencing; Referenceproteome; Ribonucleoprotein; Ribosomalprotein; RNA-binding; rRNA-binding
Protein Sequence
 METIAKHRHA RSSAQKVRLV ADLIRGKKVS QALDILTYTN KKAAVLVKKV LESAIANAEH 60
 NDGADIDDLK VTKIFVDEGP SMKRIMPRAK GRADRILKRT SHITVVVSDR 110
  GO:0022625   C:cytosolic large ribosomal subunit IDA:EcoCyc
  GO:0019843   F:rRNA binding IEA:UniProtKB-HAMAP
  GO:0003735   F:structural constituent of ribosome IEA:InterPro
  GO:0046677   P:response to antibiotic IEA:UniProtKB-KW
  GO:0006412   P:translation IEA:UniProtKB-HAMAP
  IPR001063   Ribosomal_L22.
  IPR018260   Ribosomal_L22/L17_CS.
  IPR005727   Ribosomal_L22_bac/chlpt-type.
  PF00237   Ribosomal_L22.
  PS00464   RIBOSOMAL_L22.