※ Protein Information
Tag Content
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Lipid A export ATP-binding/permease protein MsbA
Protein Synonyms/Alias
 
Gene Name
 msbA
Gene Synonyms/Alias
 b0914, JW0897
Created Date
 3-June-2014
Organism
 Escherichia coli (strain K12)
NCBI Taxa ID
 83333
Phosphorylation
Position
Peptide
Code
Type
References
378 TVALVGRSGSGKSTI S HTP [1]
Reference
 [1]Global dynamics of the Escherichia coli proteome and phosphoproteome during growth in minimal medium.
 Soares NC,Spät P,Krug K,Macek B
 J. Proteome Res. 2013, Jun, 7;12(6):2611-21. [PMID:23590516]
Functional Description From UniProt
 FUNCTION: Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation
Sequence Annotation From UniProt
 TRANSMEM 63 83 Helical; (Potential)
 TRANSMEM 140 162 Helical; (Potential)
 TRANSMEM 167 186 Helical; (Potential)
 TRANSMEM 253 273 Helical; (Potential)
 TRANSMEM 275 295 Helical; (Potential)
Key Word From UniProt
 3D-structure; ATP-binding; Cellinnermembrane; Cellmembrane; Completeproteome; Hydrolase; Lipidtransport; Membrane; Nucleotide-binding; Referenceproteome; Transmembrane; Transmembranehelix; Transport
Protein Sequence
 MHNDKDLSTW QTFRRLWPTI APFKAGLIVA GVALILNAAS DTFMLSLLKP LLDDGFGKTD 60
 RSVLVWMPLV VIGLMILRGI TSYVSSYCIS WVSGKVVMTM RRRLFGHMMG MPVSFFDKQS 120
 TGTLLSRITY DSEQVASSSS GALITVVREG ASIIGLFIMM FYYSWQLSII LIVLAPIVSI 180
 AIRVVSKRFR NISKNMQNTM GQVTTSAEQM LKGHKEVLIF GGQEVETKRF DKVSNRMRLQ 240
 GMKMVSASSI SDPIIQLIAS LALAFVLYAA SFPSVMDSLT AGTITVVFSS MIALMRPLKS 300
 LTNVNAQFQR GMAACQTLFT ILDSEQEKDE GKRVIERATG DVEFRNVTFT YPGRDVPALR 360
 NINLKIPAGK TVALVGRSGS GKSTIASLIT RFYDIDEGEI LMDGHDLREY TLASLRNQVA 420
 LVSQNVHLFN DTVANNIAYA RTEQYSREQI EEAARMAYAM DFINKMDNGL DTVIGENGVL 480
 LSGGQRQRIA IARALLRDSP ILILDEATSA LDTESERAIQ AALDELQKNR TSLVIAHRLS 540
 TIEKADEIVV VEDGVIVERG THNDLLEHRG VYAQLHKMQF GQ 582
  GO:0016021   C:integral component of membrane IBA:RefGenome
  GO:0016020   C:membrane IDA:UniProtKB
  GO:0005886   C:plasma membrane IEA:UniProtKB-SubCell
  GO:0005524   F:ATP binding IDA:EcoCyc
  GO:0008144   F:drug binding IDA:EcoliWiki
  GO:0008289   F:lipid binding IDA:EcoliWiki
  GO:0005319   F:lipid transporter activity IMP:EcoCyc
  GO:0034040   F:lipid-transporting ATPase activity IDA:EcoliWiki
  GO:0015437   F:lipopolysaccharide-transporting ATPase activity IDA:EcoCyc
  GO:1901264   P:carbohydrate derivative transport IDA:GOC
  GO:0006869   P:lipid transport IMP:EcoCyc
  GO:0055085   P:transmembrane transport IBA:RefGenome
  IPR003593   AAA+_ATPase.
  IPR011527   ABC1_TM_dom.
  IPR003439   ABC_transporter-like.
  IPR017871   ABC_transporter_CS.
  IPR011917   ABC_transpr_lipidA.
  IPR001140   ABC_transptr_TM_dom.
  IPR027417   P-loop_NTPase.
  PF00664   ABC_membrane.
  PF00005   ABC_tran.
  SM00382   AAA.
  PS50929   ABC_TM1F.
  PS00211   ABC_TRANSPORTER_1.
  PS50893   ABC_TRANSPORTER_2.
  PS51239   MSBA.