※ Protein Information
Tag Content
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Stage 0 sporulation protein A homolog
Protein Synonyms/Alias
 
Gene Name
 spo0A
Gene Synonyms/Alias
 CA_C2071
Created Date
 3-June-2014
Organism
 Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)
NCBI Taxa ID
 272562
Phosphorylation
Position
Peptide
Code
Type
References
137 SNSEQKRSYQVEEKE S HTP [1]
239 HAIEVAWSRGQVETI S HTP [1]
Reference
 [1]Phosphoproteomic investigation of a solvent producing bacterium Clostridium acetobutylicum.
 Bai X,Ji Z
 Appl. Microbiol. Biotechnol. 2012, Jul;95(1):201-11. [PMID:22627760]
Functional Description From UniProt
 FUNCTION: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process (By similarity)
Sequence Annotation From UniProt
 MOD_RES 58 58 4-aspartylphosphate (By similarity)
Key Word From UniProt
 Activator; Calcium; Completeproteome; Cytoplasm; DNA-binding; Metal-binding; Phosphoprotein; Referenceproteome; Repressor; Sporulation; Transcription; Transcriptionregulation; Two-componentregulatorysystem
Protein Sequence
 MESRKISVLI ADDNKEFCNI LNDYLLNQSD MIVVGIAKDG VEALKLIENK KPDLVVLDII 60
 MPRLDGLGVL EKLNNKDAEN LPRIIVLSAV GQDKITQRAI TLGADYYVVK PFDMDVFTNR 120
 IREMFNNTIS NSEQKRSYQV EEKEASFAGT IANDVYSDNI GNKAVDLESE ITSIIHQIGV 180
 PAHIKGYMYL REAITMVVNN MELLSAVTKE LYPSIAKKYN TTASRVERAI RHAIEVAWSR 240
 GQVETINKLF GYTINNGKGK PTNSEFIAMI ADKLRLKNKV S 281
  GO:0005737   C:cytoplasm IEA:UniProtKB-SubCell
  GO:0005509   F:calcium ion binding IEA:InterPro
  GO:0003677   F:DNA binding IEA:UniProtKB-KW
  GO:0000156   F:phosphorelay response regulator activity IEA:InterPro
  GO:0003700   F:sequence-specific DNA binding transcription factor activity IEA:InterPro
  GO:0051606   P:detection of stimulus IEA:InterPro
  GO:0042173   P:regulation of sporulation resulting in formation of a cellular spore IEA:InterPro
  GO:0030435   P:sporulation resulting in formation of a cellular spore IEA:UniProtKB-KW
  GO:0006351   P:transcription, DNA-templated IEA:UniProtKB-KW
  IPR011006   CheY-like_superfamily.
  IPR016032   Sig_transdc_resp-reg_C-effctor.
  IPR001789   Sig_transdc_resp-reg_receiver.
  IPR014879   Spo0A_C.
  IPR012052   Spore_0_A.
  IPR011991   WHTH_DNA-bd_dom.
  PF00072   Response_reg.
  PF08769   Spo0A_C.
  SM00448   REC.
  PS50110   RESPONSE_REGULATORY.