※ Protein Information
Tag Content
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein translocase subunit SecY
Protein Synonyms/Alias
 
Gene Name
 secY
Gene Synonyms/Alias
 Saci_0574
Created Date
 3-June-2014
Organism
 Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)
NCBI Taxa ID
 330779
Phosphorylation
Position
Peptide
Code
Type
References
110 LTTQEGKSKFTQAEK S HTP [1]
Reference
 [1]Archaeal signal transduction: impact of protein phosphatase deletions on cell size, motility, and energy metabolism in Sulfolobus acidocaldarius.
 Reimann J,Esser D,Orell A,Amman F,Pham TK,Noirel J,Lindås AC,Bernander R,Wright PC,Siebers B,Albers SV
 Mol. Cell Proteomics 2013, Dec;12(12):3908-23. [PMID:24078887]
Functional Description From UniProt
 FUNCTION: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
Sequence Annotation From UniProt
 TRANSMEM 21 47 Helical; Name=Helix 1; (By similarity)
 TRANSMEM 61 89 Discontinuously helical; Name=Helix 2 (By similarity)
 TRANSMEM 111 134 Helical; Name=Helix 3; (By similarity)
 TRANSMEM 143 167 Helical; Name=Helix 4; (By similarity)
 TRANSMEM 175 193 Helical; Name=Helix 5; (By similarity)
 TRANSMEM 237 258 Helical; Name=Helix 6; (By similarity)
 TRANSMEM 284 305 Helical; Name=Helix 7; (By similarity)
 TRANSMEM 342 361 Helical; Name=Helix 8; (By similarity)
 TRANSMEM 405 423 Helical; Name=Helix 9; (By similarity)
 TRANSMEM 427 441 Helical; Name=Helix 10; (By similarity)
Key Word From UniProt
 Cellmembrane; Completeproteome; Membrane; Proteintransport; Translocation; Transmembrane; Transmembranehelix; Transport
Protein Sequence
 MGFMDFLAKM GENLPAVSKP KDKPTLTRKL LWTFIGLIVY LLMASIPLYG VTSSNSFLSN 60
 FLAQQIIFAS SQGTLAQLGI GPVITSGLIM QILVGSKLIN VDLTTQEGKS KFTQAEKALA 120
 LIFIIVESSL FGYVFTRATS NILLPIIVVV QLIIASYIIL LLDEMIQKGW GLGSGVSLFI 180
 MAGIMKVIFW NMFGIVSVQS QNLPVGFFPL LVSYITSGRN LQEIVLNTSS TTPYQPDLIG 240
 LIATVGLTIL IVYLVNTNIY IPVTTQRLRG IRTTVPLNFL YVSSIPVIFV SVLGADIQLF 300
 ASLANSISNS ASGILTDIAN AFFFPPQGVP HSVYALVVDP VGAAIYAAVF IVLSIVFGML 360
 WIDVAGLDPK TQAEQMIRSG IEIPGMRTNP RIIEGILSKY IYALGFFSSL IVGLIAVVAT 420
 FLGTYGTGVG LLLAITIAMQ YYNLLAYERT LEMYPLLKRI VGE 463
  GO:0016021   C:integral component of membrane IEA:UniProtKB-KW
  GO:0005622   C:intracellular IEA:GOC
  GO:0005886   C:plasma membrane IEA:UniProtKB-SubCell
  GO:0065002   P:intracellular protein transmembrane transport IEA:UniProtKB-HAMAP
  GO:0006605   P:protein targeting IEA:UniProtKB-HAMAP
  IPR026593   SecY.
  IPR002208   SecY/SEC61-alpha.
  IPR023201   SecY_su_dom.
  IPR019561   Translocon_Sec61/SecY_plug_dom.
  PF10559   Plug_translocon.
  PF00344   SecY.
  PS00755   SECY_1.
  PS00756   SECY_2.